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Displaying results 691 - 700 of 1803 in total
  1. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    In 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers. … The N-2-cyanoethyl substituent was once believed to be resistant to cleavage, because fenproporex -- once recommended as an obesity treatment for patients with cardiovascular disease -- was originally

  2. Indication

    Algodystrophy

    go.drugbank.com/conditions/DBCOND0034820
    Drugs: Neridronic Acid
    Synonyms: Complex regional pain syndrome type I, Complex regional pain syndrome
  3. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    They were one of the first to prescribe cardiac glycosides, according to ancient literature dating as early as the 1250s.[A178240] … Digoxin is one of the oldest cardiovascular medications used today.[A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.

  4. Target

    Vitamin K epoxide reductase complex subunit 1

    go.drugbank.com/bio_entities/BE0000713
    TargetEnzymeHumans

    Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K.

    Polypeptides: Vitamin K epoxide reductase complex subunit 1
  5. Target

    H subunit of photosynthetic reaction center complex

    go.drugbank.com/bio_entities/BE0003883
    TargetThermochromatium tepidum

    Polypeptides: H subunit of photosynthetic reaction center complex
  6. Target

    ATP synthase F(0) complex subunit a

    go.drugbank.com/bio_entities/BE0009014
    TargetHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit a, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated

    Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit a
  7. Target

    Target of rapamycin complex 2 subunit MAPKAP1

    go.drugbank.com/bio_entities/BE0018900
    TargetHumans

    probably by activating one or more Rho-type guanine nucleotide exchange factors (PubMed:15467718). mTORC2 promotes the serum-induced formation of stress-fibers or F-actin (PubMed:15467718). … Inhibits HRAS and KRAS independently of mTORC2 complex (PubMed:17303383, PubMed:34380736, PubMed:35522713).

    Polypeptides: Target of rapamycin complex 2 subunit MAPKAP1
  8. Drug

    Calcium threonate

    go.drugbank.com/drugs/DB11168
    ApprovedWithdrawn

    Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calciu...

    Mixtures: Folcaps Care One, UltimateCare ONE NF
  9. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ...

    Mixtures: Se-Natal One, Virt-Care OneProducts: Care One Calcium Antacid
  10. Target

    Integrase, catalytic core

    go.drugbank.com/bio_entities/BE0003386
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Integrase, catalytic core