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Displaying results 7051 - 7060 of 9715 in total
  1. Drug

    Acitretin

    go.drugbank.com/drugs/DB00459
    ApprovedInvestigational

    It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

  2. Drug

    Nabumetone

    go.drugbank.com/drugs/DB00461
    Approved

    [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).

  3. Drug

    Enoxacin

    go.drugbank.com/drugs/DB00467
    Approved

    A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.

  4. Drug

    Dronabinol

    go.drugbank.com/drugs/DB00470
    ApprovedIllicitInvestigational

    From a pharmacological perspective, Cannabis' diverse receptor profile explains its potential application for such a wide variety of medical conditions. … (THCA-A) and cannabidiolic acid (CBDA), through decarboxylation reactions.

    Synonyms: 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol, 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  5. Drug

    Nitazoxanide

    go.drugbank.com/drugs/DB00507
    ApprovedInvestigationalVet approved

    Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].

    Products: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL
  6. Drug

    Alitretinoin

    go.drugbank.com/drugs/DB00523
    Approved

    Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic.

    Categories: Vitamin A
  7. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. … Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect.

    Categories: OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: L-OHP
  8. Drug

    Mephenytoin

    go.drugbank.com/drugs/DB00532
    ApprovedWithdrawn

    Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. … Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures.

  9. Drug

    Rofecoxib

    go.drugbank.com/drugs/DB00533
    ApprovedWithdrawn

    Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. … The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids.

  10. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    See toxicity section below for a complete listing of side effects. … In depressed individuals, amoxapine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index