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Grapiprant
go.drugbank.com/drugs/DB12836InvestigationalVet approvedGrapiprant, also known as AT-001 and CJ-023, is a drug from the piprant class. … These molecules were derived from acylsulfonamide and are characterized to be a novel series of para-N-acylaminomethylbenzoic acid known to be prostaglandin receptor antagonists.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingTazemetostat
go.drugbank.com/drugs/DB12887ApprovedInvestigationalTazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsProthipendyl
go.drugbank.com/drugs/DB12958InvestigationalProthipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTiapride
go.drugbank.com/drugs/DB13025InvestigationalTiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Products: TIADAL 100 MG/2 ML AMPUL, 12 ADETOteseconazole
go.drugbank.com/drugs/DB13055ApprovedInvestigational[L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. … [L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and little interaction with human cytochrome P450s.
Synonyms: (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, 2-Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl)-,(αR)Categories: Heterocyclic Compounds, 1-RingMeclocycline
go.drugbank.com/drugs/DB13092InvestigationalMeclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .
Mixtures: MECLODERM F, MECLODERM FLevosalbutamol
go.drugbank.com/drugs/DB13139Approved[Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. … The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol
Synonyms: R-salbutamol, (R)-salbutamolCategories: Adrenergic beta-2 Receptor Agonists, Cytochrome P-450 CYP3A InhibitorsClobetasone
go.drugbank.com/drugs/DB13158ApprovedClobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: AMISOL CREAM 0.05% w/w, CLOBUTRATE CREAM 0.05% W/WZofenopril
go.drugbank.com/drugs/DB13166ApprovedInvestigationalZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Mixtures: ZOFENOPRIL E IDROCLOROTIAZIDE EG, ZOFENOPRIL E IDROCLOROTIAZIDE MYLANValerian
go.drugbank.com/drugs/DB13196ApprovedValerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance. … Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood.
Mixtures: S. R. Formula, Lapidar 7 TabProducts: Sleep-eze V Natural Caplets