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Displaying results 721 - 730 of 1803 in total
  1. Target

    ATP synthase F(0) complex subunit e, mitochondrial

    go.drugbank.com/bio_entities/BE0009021
    TargetHumans

    Part of the complex F(0) domain (PubMed:37244256) … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).

    Polypeptides: ATP synthase F(0) complex subunit e, mitochondrialFunction: protein-containing complex binding
  2. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

    Mixtures: Care One Sinus, Facol Classic One
  3. Drug

    Selinexor

    go.drugbank.com/drugs/DB11942
    ApprovedInvestigational

    The use of selinexor in combination with [bortezomib] and [dexamethasone] was approved by Health Canada in June 2022 for the treatment of multiple myeloma in adult patients who have received at least one

  4. Drug

    Mavacamten

    go.drugbank.com/drugs/DB14921
    ApprovedInvestigational

    It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.

  5. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic...

  6. Drug

    Acalabrutinib

    go.drugbank.com/drugs/DB11703
    ApprovedInvestigational

    kinase (BTK) inhibitor indicated for the treatment of chronic lymphocytic leukemia, small lymphocytic lymphoma, and in adult patients with Mantle cell lymphoma (MCL) who have already received at least one

  7. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    Benzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond ...

    Mixtures: DUAC Once Daily Gel, CLINDOXYL Once Daily GelProducts: All-IN-one
  8. Drug

    Pyrvinium

    go.drugbank.com/drugs/DB06816
    ApprovedInvestigationalWithdrawn

    Pyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under inves...

  9. Drug

    Vanzacaftor

    go.drugbank.com/drugs/DB18373
    ApprovedInvestigational

    Vanzacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It is used alongside other CFTR correctors and CFTR potentiators to increase the quantity and function of CFTR at the cell surface in p...

  10. Drug

    Navepegritide

    go.drugbank.com/drugs/DB17824
    ApprovedInvestigational

    [L56058] Developed to address the clinical limitations of daily therapies, the pegylated nature of navepegritide allows for once-weekly dosing while providing sustained systemic exposure to CNP, which