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Displaying results 721 - 730 of 10000 in total
  1. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Products: Ag-apixaban, Apaclot 5 mg Film Kaplı Tablet, 60 ADET
  2. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]

    Mixtures: Etrafon A Tab, Etrafon F TabCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, P-glycoprotein substrates with a Narrow Therapeutic Index
  3. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. … It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency.

    Products: IFA-DIETY A. P.
  4. Drug

    Empagliflozin

    go.drugbank.com/drugs/DB09038
    ApprovedInvestigational

    [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. … Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney.

    Mixtures: SYNJARDY 5 MG/850 MG FİLM KAPLI TABLET, 60 ADET, SYNJARDY 12.5MG/850 MG FİLM KAPLI TABLET, 60 ADETProducts: EMPANCE 25 MG FİLM KAPLI TABLET, 30 ADET, JARDIANCE 10 MG FILM KAPLI TABLET, 30 ADET
  5. Target

    Interferon gamma receptor 2

    go.drugbank.com/bio_entities/BE0000467
    TargetHumans

    Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114,...

    Synonyms: AF-1
  6. Drug

    Centella asiatica

    go.drugbank.com/drugs/DB14256
    Approved

    Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Luo De Da WholeProducts: Centellaca A Clear Relaxing Toner, GZE Watery Sun Gel
  7. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    of PAH. … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.

    Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETProducts: TADALAFIL SUN, N/a
  8. Drug

    Exebacase

    go.drugbank.com/drugs/DB16161
    Investigational

    Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).

    Synonyms: Des-met1-putative phage lysin (streptococcus phage phi891591), produced in escherichia coli, Lysin cf-301 (streptococcus suis phage)
  9. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. … [A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential.

    Mixtures: SEMİTONE 50/20 MG FILM TABLET, 10 ADET, SEMİTONE 50/20 MG FILM TABLET, 20 ADETCategories: Increased Diuresis at Loop of Henle, combinations of sulfonamides
  10. Drug

    Melperone

    go.drugbank.com/drugs/DB09224
    Investigational

    Melperone is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. … It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile.

    Products: MELPERON AL 25, MELPERON AL 100