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Displaying results 7361 - 7370 of 10000 in total
  1. Target

    Microsomal glutathione S-transferase 2

    go.drugbank.com/bio_entities/BE0002290
    TargetEnzymeHumans

    Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE (PubMed:23409838, PubMed:9278457). … Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB) (PubMed:23409838, PubMed:8703034).

    Polypeptides: Microsomal glutathione S-transferase 2Synonyms: Microsomal GST-2
  2. Target

    Glutathione S-transferase omega-2

    go.drugbank.com/bio_entities/BE0002291
    TargetHumans

    Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monometh...

    Polypeptides: Glutathione S-transferase omega-2Synonyms: GSTO 2-2, Glutathione S-transferase omega 2-2
  3. Target

    Ferredoxin-dependent glutamate synthase 2

    go.drugbank.com/bio_entities/BE0002849
    TargetSynechocystis sp. (strain PCC 6803 / Kazusa)

    Polypeptides: Ferredoxin-dependent glutamate synthase 2
  4. Target

    Cytochrome c oxidase subunit 2

    go.drugbank.com/bio_entities/BE0003385
    TargetHumans

    The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix … Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit

    Polypeptides: Cytochrome c oxidase subunit 2
  5. Target

    Alpha-1-acid glycoprotein 2

    go.drugbank.com/bio_entities/BE0003663
    TargetHumans

    Functions as a transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modu...

    Polypeptides: Alpha-1-acid glycoprotein 2Synonyms: AGP 2, OMD 2
  6. Target

    Cytochrome c oxidase subunit 2

    go.drugbank.com/bio_entities/BE0003896
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

    Polypeptides: Cytochrome c oxidase subunit 2Synonyms: Cytochrome cba3 subunit 2
  7. Target

    Proteasome subunit alpha type-2

    go.drugbank.com/bio_entities/BE0003911
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit alpha type-2Synonyms: alpha-2, Proteasome subunit alpha-2
  8. Target

    Immunoglobulin heavy variable 1-2

    go.drugbank.com/bio_entities/BE0004264
    TargetHumans

    V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...

    Polypeptides: Immunoglobulin heavy variable 1-2
  9. Target

    Polycystin-2-like protein 1

    go.drugbank.com/bio_entities/BE0008712
    TransporterHumans

    The homomeric and heteromeric channels formed by PKD1L2 and PKD1L3 are activated by low pH and Ca(2+), but opens only when the extracellular pH rises again and after the removal of acid stimulus (PubMed

    Polypeptides: Polycystin-2-like protein 1Synonyms: Polycystin-2 homolog, Polycystic kidney disease 2-like 1 protein
  10. Target

    Cyclin-dependent kinase-like 2

    go.drugbank.com/bio_entities/BE0009423
    TargetHumans

    Polypeptides: Cyclin-dependent kinase-like 2