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KB3305
go.drugbank.com/drugs/DB06349ExperimentalKB3305 is an investigational liver selective antagonist for the glucocorticoid receptor, developed by Karo Bio for the treatment of Type 2 Diabetes.
Synonyms: (4R)-4-((3S,5R,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-DIHYDROXY-3-(2-(4-((8S,11R,13S,14S,17S)-17-HYDROXY-13-METHYL-3-OXO-17-PROP-1-YNYL-1,2,6,7,8,11,12,14,15,16-DECAHYDROCYCLOPENTA(A)PHENANTHREN-11-YL)-N-METHYL-ANILINO, 3.BETA.,5.BETA.,7.ALPHA.,12.ALPHA.)-7,12-DIHYDROXY-3-(2-((4-((11.BETA.,17.BETA.)-17-HYDROXY-3-OXO-17-(1-PROPYN-1-YL)ESTRA-4,9-DIEN-11-YL)PHENYL)METHYLAMINO)ETHOXY)CHOLAN-24-OIC ACIDPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol is a colorless liquid with a pleasant odor. … Phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and a low water solubility and evaporation rate.
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, HydroGold 9Synonyms: 1-Hydroxy-2-phenoxyethane, 2-phenoxyethanolMagnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigational[A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559] … Magnesium is classified as an alkaline earth metal and has 2 hydration shells.
Mixtures: One A Day Tab, Extra Once A DayProducts: MAGNEROT A 500 BEUTEL, MAGNEROT A 120 KAUTABLBiliverdin reductase A
go.drugbank.com/bio_entities/BE0000741TargetEnzymeHumansReduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor (PubMed:10858451, PubMed:7929092, PubMed:8424666,
Polypeptides: Biliverdin reductase ASynonyms: BVR AApolipoprotein A-II
go.drugbank.com/bio_entities/BE0000922TargetHumansMay stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism
Polypeptides: Apolipoprotein A-IIThromboxane-A synthase
go.drugbank.com/bio_entities/BE0001893TargetHumansCatalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:11097184, PubMed:11297515, PubMed:22735388, … Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same
Polypeptides: Thromboxane-A synthaseAlpha-galactosidase A
go.drugbank.com/bio_entities/BE0002422TargetEnzymeHumansCatalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome
Polypeptides: Alpha-galactosidase ASynonyms: Alpha-D-galactosidase ASurface protein A
go.drugbank.com/bio_entities/BE0002809TargetNeisseria meningitidisPolypeptides: Surface protein AApolipoprotein A-I
go.drugbank.com/bio_entities/BE0003449CarrierTargetEnzymeHumansParticipates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase
Polypeptides: Apolipoprotein A-I