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Displaying results 741 - 750 of 3732 in total
  1. Drug

    Chamomile

    go.drugbank.com/drugs/DB14357
    Approved

    Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  2. Drug

    Prothrombin

    go.drugbank.com/drugs/DB11311
    ApprovedInvestigational

    Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.

    Mixtures: UMAN COMPLEX, UMAN COMPLEX
  3. Drug

    Polyethylene glycol 300

    go.drugbank.com/drugs/DB11161
    Approved

    Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used i...

    Categories: P-glycoprotein inhibitors
  4. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160].

    Mixtures: Corzall PE
  6. Target

    Type-1 angiotensin II receptor

    go.drugbank.com/bio_entities/BE0000062
    TargetHumans

    Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed:15611106, PubMed:1567413, PubMed:25913193, PubMed:26420482 … The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers

    Polypeptides: Type-1 angiotensin II receptorSynonyms: AT1 receptor, Angiotensin II type-1 receptor
  7. Target

    Peroxisome proliferator-activated receptor gamma

    go.drugbank.com/bio_entities/BE0000215
    TargetHumans

    Ligand-activated transcription factor that forms obligate heterodimers with the retinoic acid receptor and acts as a key regulator of biological processes, such as adipocyte differentiation, lipid metabolism … Ligand-binding results in a conformational change in the receptor, promoting dissociation of repressors and recruitment of coactivators, and subsequent activation of target gene expression (PubMed:16150867

    Polypeptides: Peroxisome proliferator-activated receptor gammaSynonyms: Nuclear receptor subfamily 1 group C member 3
  8. Target

    Interferon alpha/beta receptor 2

    go.drugbank.com/bio_entities/BE0000385
    TargetHumans

    Together with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) (PubMed:10049744, PubMed:10556041, PubMed:21854986, PubMed:26424569

    Polypeptides: Interferon alpha/beta receptor 2Synonyms: IFN-alpha/beta receptor 2, Type I interferon receptor 2
  9. Target

    Glutamate receptor ionotropic, NMDA 2C

    go.drugbank.com/bio_entities/BE0000454
    TargetHumans

    Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:26875626, PubMed:36309015). Particip...

    Polypeptides: Glutamate receptor ionotropic, NMDA 2CSynonyms: N-methyl D-aspartate receptor subtype 2C, Glutamate [NMDA] receptor subunit epsilon-3
  10. Target

    Atrial natriuretic peptide receptor 1

    go.drugbank.com/bio_entities/BE0000556
    TargetHumans

    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis (PubMed:39543315).

    Polypeptides: Atrial natriuretic peptide receptor 1Synonyms: Atrial natriuretic peptide receptor type A