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Displaying results 741 - 750 of 10000 in total
  1. Drug

    Bromhexine

    go.drugbank.com/drugs/DB09019
    ApprovedInvestigational

    It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

    Synonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamineMixtures: GLICERTOX N F, TO-FLEM (GUAYACOLATO+BROMHEXINA)
  2. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    It is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.

    Mixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein substrates
  3. Drug

    CTX110

    go.drugbank.com/drugs/DB18626
    Investigational

    CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.

    Synonyms: allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen
  4. Indication

    Hypophosphatemic Rickets

    go.drugbank.com/conditions/DBCOND0037223
    Drugs: Alfacalcidol
    Synonyms: HPDR I - Hypophosphatemic vitamin D-resistant rickets, HPDR I - Hypophosphataemic vitamin D-resistant rickets
  5. Indication

    Neurofibromatosis Type 1

    go.drugbank.com/conditions/DBCOND0029664
    Drugs: Mirdametinib · Selumetinib
    Synonyms: Neurofibromatosis I, Neurofibromatosis Type I
  6. Drug

    Meradimate

    go.drugbank.com/drugs/DB11096
    Approved

    [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products. … Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter.

    Synonyms: Menthyl-O-aminobenzoateMixtures: Body Armor Sun 'n Bug Block, Nutriance Uv Control Skin Protection Creme SPF 8
  7. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [A265040,A265045] It works by targeting B-cell-specific CD19 surface markers present on malignant B cells. … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Synonyms: A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING O, AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODINGCategories: Genetically-modified Autologous T Cells, CD19-Directed Genetically Modified Autologous T-cell Immunotherapies
  8. Target

    Flavohemoprotein

    go.drugbank.com/bio_entities/BE0001704
    TargetCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

    Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various

    Synonyms: NO oxygenase
  9. Indication

    Myeloproliferative Disorders

    go.drugbank.com/conditions/DBCOND0029888
    Drugs: Imatinib
    Synonyms: Myeloproliferative disease, no ICD-O subtype, Chronic myeloproliferative disease, no ICD-O subtype
  10. Indication

    Trigeminal Neuralgia (TN)

    go.drugbank.com/conditions/DBCOND0081925
    Drugs: Botulinum toxin type A · Methotrimeprazine · Pyridoxine
    Synonyms: Trigeminal neuralgia [no drugs here] (disorder)