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Displaying results 741 - 750 of 10000 in total
  1. Drug

    Promethazine

    go.drugbank.com/drugs/DB01069
    ApprovedInvestigational

    Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946. … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.

    Synonyms: N,N,α-trimethyl-10H-phenothiazine-10-ethanamine, N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamineProducts: Promethazine HCl Inj USP, Promethazine HCl Inj 28.2mg/ml
  2. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. … [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline.

    Synonyms: N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)Products: Gravol Im, Gravol IV Ampoules
  3. Drug

    Isoflurane

    go.drugbank.com/drugs/DB00753
    ApprovedInvestigationalVet approved

    A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

    Products: Forane Liq Inh
  4. Drug

    Bevacizumab

    go.drugbank.com/drugs/DB00112
    ApprovedInvestigational

    bevacizumab a therapeutic role in both oncology and ophthalmology. … [A286054] In 2004, bevacizumab (Avastin) gained FDA approval and became the first antiangiogenic agent introduced to the market, indicated in combination with chemotherapy regimens specific to the type

    Products: BEVAX 100MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, BEVAX 400MG/16 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET
  5. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]

    Mixtures: AMINOPLASMAL 15% IN 500ML GLASS BOTTLE, AKE 1100 GLUKOZLU IV SOLOSYONU, 500 MLCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Daptomycin

    go.drugbank.com/drugs/DB00080
    ApprovedInvestigational

    [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil samples from Mount Ararat in Turkey. … [A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing

    Products: Daptomycin in Sodium Chloride
  7. Drug

    Clonazepam

    go.drugbank.com/drugs/DB01068
    ApprovedIllicitInvestigational

    [FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being first patented in 1960 and then released for sale from Roche in the US in 1975,[T469,T472] clonazepam has experienced a storied history … in the treatment of the aforementioned medical conditions.

    Products: RIVOTRIL 1 MG/1 ML IV ÇÖZELTİ İÇEREN AMPUL, 5 ADET
  8. Drug

    Cimetidine

    go.drugbank.com/drugs/DB00501
    ApprovedInvestigational

    It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy. … A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions.

    Synonyms: N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidineProducts: Cimetidine in Sodium Chloride, Tagamet Inj 150mg/ml
  9. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Products: Pontocaine Pws Inj 20mg/amp
  10. Target

    Linear primary-alkylsulfatase

    go.drugbank.com/bio_entities/BE0003744
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    In addition, contributes to the in vivo virulence of P.aeruginosa by playing a central role in the degradation of mucin, a glycoprotein that is the primary component of the mucus overlaying the host epithelial … Plays a role in the degradation of both protein and carbohydrate moieties in mucin via the release of sulfate from mucin, D-galactose 6-sulfate (Gal-6S) and N-acetyl-D-glucosamine 6-sulfate (GlcNAc-6S)

    Polypeptides: Linear primary-alkylsulfataseSynonyms: Type III linear primary-alkylsulfatase