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Displaying results 7571 - 7580 of 10000 in total
  1. Drug

    Sofnobrutinib

    go.drugbank.com/drugs/DB21626
    Experimental

    Sofnobrutinib is a small molecule drug. The usage of the INN stem '-brutinib' in the name indicates that Sofnobrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor. … Sofnobrutinib has a monoisotopic molecular weight of 498.19 Da.

  2. Drug

    Lacutoclax

    go.drugbank.com/drugs/DB21657
    Investigational

    Lacutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Lacutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Lacutoclax has a monoisotopic molecular weight of 922.36 Da.

  3. Drug

    Vilzemetkib

    go.drugbank.com/drugs/DB21704
    Experimental

    Vilzemetkib is a small molecule drug. The usage of the INN stem '-metkib' in the name indicates that Vilzemetkib is a MET (mesenchymal epithelial transition factor) kinase inhibitor. … Vilzemetkib has a monoisotopic molecular weight of 642.27 Da.

  4. Drug

    Candoxatrilat

    go.drugbank.com/drugs/DB11623
    Experimental

    A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure. … A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy

  5. Drug

    TAS-102

    go.drugbank.com/drugs/DB08937
    Investigational

    TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer.

  6. Drug

    Basic Fibroblast Growth Factor

    go.drugbank.com/drugs/DB14131
    Investigational

    Although it is not approved for use in Canada or the USA, bFGF is currently undergoing investigation in a number of clinical trials. … The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages.

  7. Drug

    R-30490

    go.drugbank.com/drugs/DB09179
    Experimental

    R-30490 is an opioid related to carfentanil used as an animal tranquilizer. … It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives.

  8. Drug

    GC-373

    go.drugbank.com/drugs/DB15797
    Experimental

    It is an inhibitor of M<sup>pro</sup> (otherwise known as 3CL<sup>pro</sup>), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription[A219036 … GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, [GC-376 free acid][A219031,A219036].

  9. Drug

    Flurocitabine

    go.drugbank.com/drugs/DB20317
    Experimental

    The usage of the INN stem '-citabine' in the name indicates that Flurocitabine is a nucleoside antiviral or antineoplastic agent, cytarabine or azacitidine derivative. … Flurocitabine has a monoisotopic molecular weight of 243.07 Da.

  10. Drug

    Acloproxalap

    go.drugbank.com/drugs/DB21553
    Investigational

    Acloproxalap is under investigation in clinical trial NCT06685692 (A Clinical Trial Investigating the Safety and Efficacy of Subjects With Alcohol Associated Hepatitis (Part 1)). … Acloproxalap has a monoisotopic molecular weight of 202.11 Da.