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Displaying results 751 - 760 of 10000 in total
  1. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … well as athlete's foot [A174097].

    Mixtures: LINDAZOL-2 ®, LINDAZOL-2 ®Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  2. Indication

    Seizure Disorders

    go.drugbank.com/conditions/DBCOND0046733
    Drugs: Ganaxolone · Midazolam
    Synonyms: Seizure disorder(s)
  3. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

    Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte SInternational brands: Slow-K, Micro-K
  4. Drug

    Arnica montana

    go.drugbank.com/drugs/DB14297
    Investigational

    Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: European Arnica Whole
  5. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0001684
    TargetHumans

    Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity)

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  6. Target

    Cytosol aminopeptidase

    go.drugbank.com/bio_entities/BE0003882
    TargetHumans

    For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. … Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status

    Synonyms: Peptidase S, Cysteinylglycine-S-conjugate dipeptidase
  7. Target

    Complement C1s subcomponent

    go.drugbank.com/bio_entities/BE0001529
    TargetEnzymeHumans

    Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the ...

    Synonyms: Complement component 1 subcomponent s
  8. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)

    Synonyms: Peptidyl-cysteine S-nitrosylase GAPDH
  9. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol is on the World Health Organization's List of Essential Medicines. … It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics.

    Synonyms: 2-chloro-5-hydroxy-m-xylene, 2-Chloro-m-xylenolMixtures: Cortane-B, Cortaine -B Aqueous
  10. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Synonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, Taxol ACategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index