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Dalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationaland methicillin-resistant strains), S. pyogenes, S. agalactiae, S. dysgalactiae, the S. anginosus group (including S. anginosus, S. intermedius, and S. constellatus), and Enterococcus faecalis (vancomycin … Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072
Products: Dalbavancin Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Dalbavancin ratiopharm 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigationalIsotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Synonyms: Neovitamin A acid, 13-cis-Vitamin A acidMixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalRLS is a sleep-related disorder characterized by unpleasant sensations in the lower extremities, often accompanied by an uncontrollable urge to move the legs [A176876]. … It was first approved by the FDA in 1997 [L5882].
Synonyms: (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamineInternational brands: Sifrol ERDesvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigationalDesvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: O-desmethylvenlafaxineTolbutamide
go.drugbank.com/drugs/DB01124ApprovedIt is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor.
Categories: Genito Urinary System and Sex Hormones, Cytochrome P-450 SubstratesSynonyms: 3-(p-Tolyl-4-sulfonyl)-1-butylurea, 1-Butyl-3-(p-tolylsulfonyl)ureaChenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalChenodeoxycholic acid is a bile acid naturally found in the body. … It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: CETEİX 250 MG SERT KAPSÜL, 100 ADET, KENDEO 250 MG SERT KAPSÜL, 100 ADETIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B<sub>2</sub> receptors with a similar affinity to bradykinin.
Products: ICATIBANT EG, İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
Mixtures: DAIVOBET® GEL 50 MCG + 0.5 MG/ G, DAIVOBET GEL 50 MCG + 0.5 MG/ GCategories: Sex Hormones and Insulins, Cytochrome P-450 SubstratesNeostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.
Synonyms: m-Trimethylammoniumphenyldimethylcarbamate, (m-Hydroxyphenyl)trimethylammonium dimethylcarbamateProducts: PLANTIGMIN 0,5 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 50 ADET, NEOSTİGMİN 0,5 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, , 50 ADETEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersProducts: ELETRIPTAN EG, Eletop 20 mg-Filmtabletten