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N-arachidonyl glycine receptor
go.drugbank.com/bio_entities/BE0002304TargetHumansG protein-coupled receptor (GPCR) that plays a role in diverse physiological processes particularly within the immune and nervous systems (PubMed:21732409, PubMed:26195725).
Polypeptides: N-arachidonyl glycine receptorSynonyms: NAGly receptor, G protein-coupled receptor 18Anthrax toxin receptor 1
go.drugbank.com/bio_entities/BE0003447TargetHumansMay also act as a receptor for PLAU. Upon ligand binding, stimulates the phosphorylation of EGFR and ERK1/2 (PubMed:30241478)
Polypeptides: Anthrax toxin receptor 1Toll-like receptor 8
go.drugbank.com/bio_entities/BE0003518TargetHumansEndosomal receptor that plays a key role in innate and adaptive immunity (PubMed:25297876, PubMed:32433612).
Polypeptides: Toll-like receptor 8Somatostatin receptor type 3
go.drugbank.com/bio_entities/BE0003529TargetHumansReceptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase
Polypeptides: Somatostatin receptor type 3Function: G protein-coupled receptor activityNuclear receptor ROR-beta
go.drugbank.com/bio_entities/BE0003554TargetHumansNuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence.
Polypeptides: Nuclear receptor ROR-betaSynonyms: Nuclear receptor RZR-beta, Retinoid-related orphan receptor-betaOxysterols receptor LXR-alpha
go.drugbank.com/bio_entities/BE0003781TargetHumansNuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920, PubMed:37478846). … Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by
Polypeptides: Oxysterols receptor LXR-alphaSynonyms: Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3Nuclear receptor ROR-alpha
go.drugbank.com/bio_entities/BE0004545TargetHumansNuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence.
Polypeptides: Nuclear receptor ROR-alphaSynonyms: Nuclear receptor RZR-alpha, RAR-related orphan receptor A5-hydroxytryptamine receptor 5A
go.drugbank.com/bio_entities/BE0004688TargetHumansAlso functions as a receptor for ergot alkaloid derivatives and other psychoactive substances (PubMed:35835867). … G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521).
Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: Serotonin receptor 5AParathyroid hormone 2 receptor
go.drugbank.com/bio_entities/BE0004703TargetHumansThis is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. … PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity)
Polypeptides: Parathyroid hormone 2 receptorSynonyms: PTH2 receptor5-hydroxytryptamine 2 receptor
go.drugbank.com/bio_entities/BE0004881TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773). … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895, PubMed:21645528, PubMed:22300836, PubMed:35084960, PubMed:38552625).
Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: Serotonin receptor 2A, Serotonin receptor 2B