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Displaying results 761 - 770 of 10000 in total
  1. Target

    Uroporphyrinogen-III C-methyltransferase

    go.drugbank.com/bio_entities/BE0002528
    TargetPseudomonas denitrificans

    Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B...

    Synonyms: S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase
  2. Drug

    Latanoprostene bunod

    go.drugbank.com/drugs/DB11660
    Approved

    As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle glaucoma … Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure.

  3. Target

    Lactoylglutathione lyase

    go.drugbank.com/bio_entities/BE0000962
    TargetEnzymeHumans

    Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294).

    Synonyms: S-D-lactoylglutathione methylglyoxal lyase
  4. Target

    Hydroxymycolate synthase MmaA4

    go.drugbank.com/bio_entities/BE0003863
    TargetMycobacterium tuberculosis

    Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation

    Synonyms: S-adenosylmethionine-dependent methyltransferase
  5. Indication

    Primary Immune Deficiency Disorders (PIDD)

    go.drugbank.com/conditions/DBCOND0038807
    Drugs: Hyaluronidase (human recombinant)
    Synonyms: Primary Immunodeficiency Disease(s)
  6. Target

    Cyanocobalamin reductase / alkylcobalamin dealkylase

    go.drugbank.com/bio_entities/BE0002175
    TargetHumans

    Cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate (PubMed:187795...

    Synonyms: Alkylcobalamin:glutathione S-alkyltransferase
  7. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.

    Mixtures: CLAMOXIN S, LUMOXBRON-SCategories: Penicillin G, Heterocyclic Compounds, 1-Ring
  8. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments.

    Products: CLEAR S Suds, Careone Antimicrobial Foaming Hand Sp Falling Rain
  10. Target

    Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

    go.drugbank.com/bio_entities/BE0004448
    TargetHumans

    GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GS...

    Synonyms: G1 to S phase transition protein 1 homolog