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Immunoglobulin lambda variable 2-8
go.drugbank.com/bio_entities/BE0002939TargetHumansV region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin lambda variable 2-8Autoinducer 2-binding protein LsrB
go.drugbank.com/bio_entities/BE0003287TargetSalmonella typhiPart of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
Polypeptides: Autoinducer 2-binding protein LsrBSynonyms: AI-2-binding protein LsrBGamma-secretase subunit PEN-2
go.drugbank.com/bio_entities/BE0003410TargetHumansEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:12522139, PubMed:1...
Polypeptides: Gamma-secretase subunit PEN-2Synonyms: Presenilin enhancer protein 2Bcl-2-like protein 1
go.drugbank.com/bio_entities/BE0003510TargetHumansPotent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the m...
Polypeptides: Bcl-2-like protein 1Poly [ADP-ribose] polymerase 2
go.drugbank.com/bio_entities/BE0003798TargetHumansIn addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex (PubMed:27471034, PubMed:29361132) … aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'
Polypeptides: Poly [ADP-ribose] polymerase 2Synonyms: ADPRT-2, PARP-2Immunoglobulin kappa variable 2-30
go.drugbank.com/bio_entities/BE0003837TargetHumansV region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Polypeptides: Immunoglobulin kappa variable 2-30Cytochrome c oxidase subunit 2
go.drugbank.com/bio_entities/BE0003900TargetThermus thermophilusSubunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Polypeptides: Cytochrome c oxidase subunit 2Synonyms: Cytochrome cba3 subunit 2Pancreatic lipase-related protein 2
go.drugbank.com/bio_entities/BE0004027TargetEnzymeHumansIn neurons, required for the localization of the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) to neurite tips through acyl chain remodeling of membrane phospholipids (By similarity).
Polypeptides: Pancreatic lipase-related protein 2Cytochrome c oxidase subunit 2
go.drugbank.com/bio_entities/BE0004056TargetRhodobacter sphaeroidesSubunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Polypeptides: Cytochrome c oxidase subunit 2Synonyms: Cytochrome aa3 subunit 2, Oxidase aa(3) subunit 2Rho-associated protein kinase 2
go.drugbank.com/bio_entities/BE0004191TargetHumansPlays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation
Polypeptides: Rho-associated protein kinase 2Synonyms: p164 ROCK-2, Rho kinase 2