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Displaying results 771 - 780 of 10000 in total
  1. Target

    Thromboxane-A synthase

    go.drugbank.com/bio_entities/BE0001893
    TargetHumans

    Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:11097184, PubMed:11297515, PubMed:22735388, … Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same

    Polypeptides: Thromboxane-A synthase
  2. Target

    Alpha-galactosidase A

    go.drugbank.com/bio_entities/BE0002422
    TargetEnzymeHumans

    Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome

    Polypeptides: Alpha-galactosidase ASynonyms: Alpha-D-galactosidase A
  3. Target

    Surface protein A

    go.drugbank.com/bio_entities/BE0002809
    TargetNeisseria meningitidis

    Polypeptides: Surface protein A
  4. Target

    Apolipoprotein A-I

    go.drugbank.com/bio_entities/BE0003449
    CarrierTargetEnzymeHumans

    Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase

    Polypeptides: Apolipoprotein A-I
  5. Target

    Prelamin-A/C

    go.drugbank.com/bio_entities/BE0010877
    TargetHumans

    Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner … Lamin A and C also regulate matrix stiffness by conferring nuclear mechanical properties (PubMed:23990565, PubMed:25127216).

    Polypeptides: Prelamin-A/C
  6. Drug

    Hiltonol

    go.drugbank.com/drugs/DB17293
    Investigational

    Synonyms: 5'-cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and l-lysine homopolymer, 5'-inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and l-lysine homopolymerCategories: Poly C, Poly I
  7. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.

    Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-A
  8. Target

    Probable arabinosyltransferase A

    go.drugbank.com/bio_entities/BE0000034
    TargetMycobacterium tuberculosis

    Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.

    Polypeptides: Probable arabinosyltransferase A
  9. Target

    Aurora kinase A

    go.drugbank.com/bio_entities/BE0000991
    TargetHumans

    Plays a role in microtubule remodeling during neurite extension (PubMed:19668197). … Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome

    Polypeptides: Aurora kinase ASynonyms: Serine/threonine-protein kinase aurora-A
  10. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001362
    TargetChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein