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Tylosin
go.drugbank.com/drugs/DB11475ExperimentalVet approvedTylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. … It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence. … It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics.
Cycloguanil
go.drugbank.com/drugs/DB14763ApprovedCycloguanil is the active metabolite of proguanil.
Categories: Antiparasitic Products, Insecticides and RepellentsAutologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
REC-994
go.drugbank.com/drugs/DB15616InvestigationalREC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Methylthioinosine
go.drugbank.com/drugs/DB02896ExperimentalAn analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Categories: Nucleic Acids, Nucleotides, and NucleosidesRivoglitazone
go.drugbank.com/drugs/DB09200InvestigationalIt is being developed by Daiichi Sankyo Co.
AG0302-COVID19
go.drugbank.com/drugs/DB16435InvestigationalSponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].
Oleic monoethanolamide
go.drugbank.com/drugs/DB16495InvestigationalCategories: Cannabinoids and similars, Hormones, Hormone Substitutes, and Hormone AntagonistsISP-001
go.drugbank.com/drugs/DB18501InvestigationalISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and delivery of alpha-L-iduronidase.