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Displaying results 7871 - 7880 of 8412 in total

Drug
Kitasamycin
go.drugbank.com/drugs/DB09309
Experimental
Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
Norethynodrel
go.drugbank.com/drugs/DB09371
Approved
A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combin...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Grapefruit
go.drugbank.com/drugs/DB10534
Approved
Grapefruit allergenic extract is used in allergenic testing.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
Isoflurane
go.drugbank.com/drugs/DB00753
ApprovedInvestigationalVet approved
A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
Drug
Benzquinamide
go.drugbank.com/drugs/DB00767
ApprovedWithdrawn
Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine re...
Categories: P-glycoprotein inhibitors
Drug
Roxithromycin
go.drugbank.com/drugs/DB00778
ApprovedInvestigationalWithdrawn
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, partic...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsInternational brands: Pu Hong, Bi Ai Di
Drug
Rosoxacin
go.drugbank.com/drugs/DB00817
Approved
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Conivaptan
go.drugbank.com/drugs/DB00872
Approved
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both is...
Synonyms: 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilideCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
Drug
Rimexolone
go.drugbank.com/drugs/DB00896
ApprovedWithdrawn
Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
Drug
Tinidazole
go.drugbank.com/drugs/DB00911
ApprovedInvestigational
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates