Identification

Summary

Grapefruit is an extract from Grapefruit used in allergy testing.

Generic Name
Grapefruit
DrugBank Accession Number
DB10534
Background

Grapefruit allergenic extract is used in allergenic testing.

Type
Biotech
Groups
Approved
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Citrus X paradisi fruit

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
GrapefruitInjection, solution0.1 g/1mLIntradermal; SubcutaneousNelco Laboratories, Inc.1972-08-29Not applicableUS flag
GrapefruitInjection, solution0.1 g/1mLIntradermal; SubcutaneousNelco Laboratories, Inc.1972-08-29Not applicableUS flag
GrapefruitSolution0.025 g/1mLIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1981-09-15Not applicableUS flag
GrapefruitInjection, solution0.05 g/1mLIntradermal; SubcutaneousNelco Laboratories, Inc.1972-08-29Not applicableUS flag
GrapefruitInjection, solution1 mL/1mLIntradermal; SubcutaneousAntigen Laboratories, Inc.1974-03-23Not applicableUS flag
GrapefruitInjection, solution1 g/20mLPercutaneous; SubcutaneousAllergy Laboratories, Inc.1972-08-29Not applicableUS flag
GrapefruitInjection, solution0.05 g/1mLIntradermal; SubcutaneousNelco Laboratories, Inc.1972-08-29Not applicableUS flag
GrapefruitInjection, solution0.05 g/1mLIntradermal; SubcutaneousAntigen Laboratories, Inc.1974-03-23Not applicableUS flag
GrapefruitInjection, solution0.10 g/1mLPercutaneousALK-Abello, Inc.1965-01-01Not applicableUS flag
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Hand SanitizerSpray0.3 mg/0.3mLTopicalSanchez, S.a. De C.v.2020-03-30Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Cellskin Clean Pine MistGrapefruit (0.05 g/100mL) + Eucalyptus oil (0.01 g/100mL) + Tea tree oil (0.01 g/100mL)SprayTopicalGtg Wellness Co., Ltd.2020-07-01Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Cellskin Clean Pine MistGrapefruit (0.05 g/100mL) + Eucalyptus oil (0.01 g/100mL) + Tea tree oil (0.01 g/100mL)SprayTopicalGtg Wellness Co., Ltd.2020-07-01Not applicableUS flag
Hand SanitizerGrapefruit (0.3 mg/0.3mL)SprayTopicalSanchez, S.a. De C.v.2020-03-30Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
O82C39RR8C
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910694
RxNav
899424
Wikipedia
Grapefruit

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SprayTopical
Injection, solutionIntradermal; Subcutaneous0.05 g/1mL
Injection, solutionIntradermal; Subcutaneous0.1 g/1mL
Injection, solutionIntradermal; Subcutaneous1 mL/1mL
Injection, solutionPercutaneous0.10 g/1mL
Injection, solutionPercutaneous; Subcutaneous1 g/20mL
SolutionIntradermal; Percutaneous; Subcutaneous0.025 g/1mL
SprayTopical0.3 mg/0.3mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Enzymes

Kind
Protein
Organism
Humans
Pharmacological action
Unknown
Actions
Inhibitor
General Function
Vitamin d3 25-hydroxylase activity
Specific Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation react...
Gene Name
CYP3A4
Uniprot ID
P08684
Uniprot Name
Cytochrome P450 3A4
Molecular Weight
57342.67 Da
References
  1. Klotz U: Interaction potential of lercanidipine, a new vasoselective dihydropyridine calcium antagonist. Arzneimittelforschung. 2002;52(3):155-61. doi: 10.1055/s-0031-1299873. [Article]

Drug created at December 01, 2015 20:04 / Updated at June 28, 2022 02:11