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Displaying results 781 - 790 of 10000 in total
  1. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0008385
    TargetStaphylococcus aureus

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  2. Target

    Repulsive guidance molecule A

    go.drugbank.com/bio_entities/BE0018257
    TargetHumans

    It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8

    Polypeptides: Repulsive guidance molecule ASynonyms: RGM domain family member A
  3. Target

    Poly(A) polymerase gamma

    go.drugbank.com/bio_entities/BE0018981
    TargetHumans

    Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA

    Polypeptides: Poly(A) polymerase gammaSynonyms: Neo-poly(A) polymerase
  4. Drug

    Oxacillin

    go.drugbank.com/drugs/DB00713
    ApprovedInvestigational

    An antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.

    Synonyms: (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5-methyl-3-phenyl-4-isoxazolyl)penicillinInternational brands: Staficilin-N
  5. Target

    Lipid A palmitoyltransferase PagP

    go.drugbank.com/bio_entities/BE0001965
    TargetEscherichia coli (strain K12)

    Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

    Polypeptides: Lipid A palmitoyltransferase PagPSynonyms: Lipid A acylation protein
  6. Target

    Dihydroorotate dehydrogenase A (fumarate)

    go.drugbank.com/bio_entities/BE0002008
    TargetLactococcus lactis subsp. cremoris

    Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.

    Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD A
  7. Target

    Group A nerve fibers

    go.drugbank.com/bio_entities/BE0009708
    TargetRat

  8. Target

    BCL11 transcription factor A

    go.drugbank.com/bio_entities/BE0019545
    TargetHumans

    May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity) … May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity).

    Polypeptides: BCL11 transcription factor A
  9. Target

    Cholecystokinin receptor type A

    go.drugbank.com/bio_entities/BE0000402
    TargetHumans

    This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system … Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system.

    Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptor
  10. Target

    Choline-phosphate cytidylyltransferase A

    go.drugbank.com/bio_entities/BE0000615
    EnzymeTargetHumans

    Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis

    Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CT A, CCT A