Search

Displaying results 781 - 790 of 10000 in total
  1. Target

    Protein S100-A2

    go.drugbank.com/bio_entities/BE0003602
    TargetHumans

    May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May a...

    Synonyms: Protein S-100L
  2. Target

    Arsenite methyltransferase

    go.drugbank.com/bio_entities/BE0005015
    TargetEnzymeHumans

    Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is redu...

    Synonyms: S-adenosyl-L-methionine:arsenic(III) methyltransferase
  3. Target

    ATP-citrate synthase

    go.drugbank.com/bio_entities/BE0009867
    TargetEnzymeHumans

    Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism

    Synonyms: ATP-citrate (pro-S-)-lyase
  4. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Mixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% MinoxidilCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Alogliptin

    go.drugbank.com/drugs/DB06203
    ApprovedInvestigational

    Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4).

    Mixtures: Alogliptin and Metformin Hydrochloride, Alogliptin and Metformin HydrochlorideCategories: metformin and alogliptin, Cytochrome P-450 Substrates
  6. Drug

    Troglitazone

    go.drugbank.com/drugs/DB00197
    ApprovedWithdrawn

    Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  7. Target

    Creatine Kinases

    go.drugbank.com/bio_entities/BE0009627
    EnzymeTargetHumans

    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energ...

    Synonyms: S-MtCKPolypeptides: Creatine kinase S-type, mitochondrial
  8. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.

    Mixtures: Percutaneous Sheath Intro Kit Ak-09810-S, Percutaneous Sheath Intro Kit Ak-09810-SCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  9. Indication

    Hodgkin's Lymphoma

    go.drugbank.com/conditions/DBCOND0030382
    Drugs: Bleomycin · Chlorambucil · Cyclophosphamide · Dacarbazine · Doxorubicin · Gemcitabine +5 more
    Synonyms: Hodgkin´s Lymphomas, Hodgkin´s Lymphoma
  10. Target

    Quinoprotein glucose dehydrogenase B

    go.drugbank.com/bio_entities/BE0001728
    TargetEnzymeAcinetobacter calcoaceticus

    Oxidizes glucose to gluconolactone.

    Synonyms: s-GDH