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Doxepin H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145423Drug actionDoxepin is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfere ...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BClozapine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145424Drug actionClozapine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfer...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BPropiomazine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145425Drug actionPropiomazine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines inter...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BCetirizine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145426Drug actionCetirizine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfe...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BTrazodone H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145430Drug actionTrazodone is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfer...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BZuclopenthixol H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145433Drug actionZuclopenthixol is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines int...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BDosulepin H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145434Drug actionDosulepin is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfer...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BAceprometazine H1 Antihistamine Neurological Sleep Action Pathway
smpdb.ca/view/SMP0145435Drug actionAceprometazine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines int...
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BGlibenclamide Action Pathway
smpdb.ca/view/SMP0000460Drug actionDepolarization causes opening of voltage-gated calcium channels, allowing calcium to enter cell. High intracellular calcium subsequently stimulate vesicle exocytosis and insulin secretion.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Gliclazide Action Pathway
smpdb.ca/view/SMP0000461Drug actionDepolarization causes opening of voltage-gated calcium channels, allowing calcium to enter cell. High intracellular calcium subsequently stimulate vesicle exocytosis and insulin secretion.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1