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Afatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalan FDA-approved test [L2939]. … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label].
Categories: Antineoplastic and Immunomodulating AgentsProducts: GIOTRIF 20MG FILM-COATED TABLETS, GIOTRIF FILM-COATED TABLETS 20MGFlucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Products: Fluclox 500 Cap 500mg, Fluclox-250 Cap 250mgClofibrate
go.drugbank.com/drugs/DB00636ApprovedWithdrawnA fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Products: Atromid-S Cap 500mg, Atromid S Cap 500mgRanibizumab
go.drugbank.com/drugs/DB01270ApprovedInvestigational[A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission (EC) in 2007.[L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. … [L41399] In August 2022, other biosimilars CIMERLI, RAIVISIO, and RANOPTO were approved by the FDA, EC, and Health Canada respectively.[L42625,L43513,L49141]
Categories: Amino Acids, Peptides, and ProteinsProducts: LUCENTIS(10MG/ML), Lucentis 10mg/ml Solution for InjectionAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]
Synonyms: N-AC, N-acetylcysteineMixtures: Levomefolate Calcium Acetylcysteine and Mecobalamin Algal, Levomefolate Calcium, Acetylcysteine, Mecobalamin and AlgalValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalValsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
Synonyms: N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine, (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valineMixtures: CARDIK - IN® 160/2.5, CARDIK - IN® 160/2.5Protamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalSince it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps … Despite the relative importance of protamine sulfate's medical indication, the medication can notoriously cause a variety of potentially rare but genuinely severe adverse effects that include systemic
Categories: Amino Acids, Peptides, and ProteinsProducts: Protamine Sulfate Inj 10mg/ml USP, Prosulf 10mg/ml Solution for InjectionHomocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0000570DiseaseSymptoms include megaloblastic anemia, and can also include developmental delays, seisures and kidney failure. Treatment with vitamin B12, as well as folates and betaine is effective. … Methionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreNitisinone
go.drugbank.com/drugs/DB00348ApprovedNitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria. … It is sold under the brand names Orfadin and Harliku. [L53253, L53258]
Categories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism ProductsProducts: TISINON 10MG KAPSÜL, 60 KAPSÜL, TISINON 20MG KAPSÜL, 60 KAPSÜLCoagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalNovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form. … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade.
Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansProducts: powder and solvent for solution for injection 2mg, NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION