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Displaying results 791 - 800 of 10000 in total
  1. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.

    Mixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTACategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, combinations of sulfonamides
  2. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men … This results in increased pulmonary or systemic blood flow in infants.[A34474,L45038,L45063]

    Synonyms: (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, PGE-1International brands: Caverject DC
  3. Drug

    Testosterone propionate

    go.drugbank.com/drugs/DB01420
    ApprovedInvestigationalVet approvedWithdrawn

    It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. … Currently, this drug has been discontinued in humans, but the vet application is still available as an OTC.[L1160]

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Malogen In Oil Liq 100mg/ml, Testosterone Propionate Inj 100mg/ml
  4. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. … On skin, it is also observed to have moisturizing actions [L1771, L1773].

    Mixtures: E-Z-gas II, MULTIGEL IICategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.

    Mixtures: LISINOPRIL E IDROCLOROTIAZIDE DOC GENERICI, LISINOPRIL E IDROCLOROTIAZIDE DOC GENERICICategories: Compounds used in a research, industrial, or household setting, Agents Acting on the Renin-Angiotensin System
  6. Target

    O-phosphoseryl-tRNA(Sec) selenium transferase

    go.drugbank.com/bio_entities/BE0002171
    TargetHumans

    Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

    Polypeptides: O-phosphoseryl-tRNA(Sec) selenium transferaseFunction: O-phosphoseryl-tRNA(Sec) selenium transferase activity
  7. Target

    Membrane-bound glycerophospholipid O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0015719
    EnzymeHumans

    May be involved in chondrocyte differentiation (By similarity) … Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid

    Polypeptides: Membrane-bound glycerophospholipid O-acyltransferase 2Synonyms: 1-acylglycerophosphate O-acyltransferase MBOAT2, 1-acylglycerophosphocholine O-acyltransferase MBOAT2
  8. Target

    Carnitine O-palmitoyltransferase 1, muscle isoform

    go.drugbank.com/bio_entities/BE0017721
    TargetHumans

    Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in

    Polypeptides: Carnitine O-palmitoyltransferase 1, muscle isoformSynonyms: Carnitine O-palmitoyltransferase I, muscle isoform
  9. Target

    Carnitine O-palmitoyltransferase 1, liver isoform

    go.drugbank.com/bio_entities/BE0000406
    TargetHumans

    Also possesses a lysine succinyltransferase activity that can regulate enzymatic activity of substrate proteins such as ENO1 and metabolism independent of its classical carnitine O-palmitoyltransferase … Plays an important role in hepatic triglyceride metabolism (By similarity).

    Polypeptides: Carnitine O-palmitoyltransferase 1, liver isoformSynonyms: Carnitine O-palmitoyltransferase I, liver isoform
  10. Drug

    Fludarabine

    go.drugbank.com/drugs/DB01073
    ApprovedInvestigational

    Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.

    Synonyms: 2-F-ARAA, 2-fluoro ARA-ACategories: Heterocyclic Compounds, 2-Ring, DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitors