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Glutathione S-transferase Mu 4
go.drugbank.com/bio_entities/BE0000812TargetHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:8203914, PubMed:8373352). Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4...
Polypeptides: Glutathione S-transferase Mu 4Synonyms: GSTM4-4, GST class-mu 4Protein-glutamine gamma-glutamyltransferase 4
go.drugbank.com/bio_entities/BE0002243EnzymeTargetHumansAssociated with the mammalian reproductive process. Catalyzes the cross-linking of proteins and the conjugation of polyamines to specific proteins in the seminal tract
Polypeptides: Protein-glutamine gamma-glutamyltransferase 4Synonyms: TGase-4, Transglutaminase-4Neuropeptide Y receptor type 4
go.drugbank.com/bio_entities/BE0002418TargetHumansThe rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13
Polypeptides: Neuropeptide Y receptor type 4DNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0003726TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA (PubMed:17375187, PubMed:20596531). Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit AProteasome subunit alpha type-4
go.drugbank.com/bio_entities/BE0003913TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...
Polypeptides: Proteasome subunit alpha type-4Synonyms: alpha-3, Proteasome subunit alpha-3Hepatocyte nuclear factor 4-alpha
go.drugbank.com/bio_entities/BE0004019TargetHumansTranscriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...
Polypeptides: Hepatocyte nuclear factor 4-alphaSynonyms: Nuclear receptor subfamily 2 group A member 1, HNF-4-alphaEphrin type-A receptor 4
go.drugbank.com/bio_entities/BE0009438TargetHumansReceptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referr...
Polypeptides: Ephrin type-A receptor 4Mitogen-activated protein kinase 4
go.drugbank.com/bio_entities/BE0009476TargetHumansPhosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5.
Polypeptides: Mitogen-activated protein kinase 4Synonyms: ERK-4, MAPK 4DNA polymerase delta subunit 4
go.drugbank.com/bio_entities/BE0020436TargetHumansWithin this complex, increases the rate of DNA synthesis and decreases fidelity by regulating POLD1 polymerase and proofreading 3' to 5' exonuclease activity (PubMed:16510448, PubMed:19074196, PubMed:20334433
Polypeptides: DNA polymerase delta subunit 4Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z)/20:3(11Z,14Z,17Z)/20:3(11Z,14Z,17Z))
smpdb.ca/view/SMP0244192MetabolicThird, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).
Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphateEnzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial