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Displaying results 801 - 810 of 10000 in total
  1. Drug

    Benzoic acid

    go.drugbank.com/drugs/DB03793
    ApprovedInvestigational

    This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. … A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Crisaborole

    go.drugbank.com/drugs/DB05219
    ApprovedInvestigational

    Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. … It is currently under development as topical treatment of psoriasis.

  3. Drug

    Ciclesonide

    go.drugbank.com/drugs/DB01410
    ApprovedInvestigational

    Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.

  4. Target

    Glycine receptor subunit beta

    go.drugbank.com/bio_entities/BE0000055
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:11929858, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:23238346, PubMed:25445488, PubMed:34473954, PubMed:8717357). Plays an important role in the down-regulatio...

    Polypeptides: Glycine receptor subunit betaSynonyms: Glycine receptor 58 kDa subunit
  5. Target

    Beta-1 adrenergic receptor

    go.drugbank.com/bio_entities/BE0000172
    TargetHumans

    G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway (PubMed:10212248, PubMed:12391161, PubMed:15358775).

    Polypeptides: Beta-1 adrenergic receptorFunction: alpha-2A adrenergic receptor binding
  6. Target

    5-hydroxytryptamine receptor 1A

    go.drugbank.com/bio_entities/BE0000291
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:22957663, PubMed:3138543, PubMed:33762731, PubMed:37935376, PubMed:37935377, PubMed:8138923, PubMed:8393041). … Also functions as a receptor for various drugs and psychoactive substances (PubMed:22957663, PubMed:3138543, PubMed:33762731, PubMed:38552625, PubMed:8138923, PubMed:8393041).

    Polypeptides: 5-hydroxytryptamine receptor 1ASynonyms: Serotonin receptor 1A
  7. Target

    5-hydroxytryptamine receptor 3A

    go.drugbank.com/bio_entities/BE0000311
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3ASynonyms: Serotonin receptor 3A, 5-hydroxytryptamine receptor 3
  8. Target

    Thyroid hormone receptor beta

    go.drugbank.com/bio_entities/BE0000315
    TargetHumans

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor betaSynonyms: Nuclear receptor subfamily 1 group A member 2
  9. Target

    Follicle-stimulating hormone receptor

    go.drugbank.com/bio_entities/BE0000387
    TargetHumans

    G protein-coupled receptor for follitropin, the follicle-stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). … Also affects hepatic cholesterol metabolism by increasing serum total and low-density-lipoprotein cholesterol (LDL-C) by inhibiting the expression of LDL receptor (LDLR) (PubMed:26583582)

    Polypeptides: Follicle-stimulating hormone receptorSynonyms: Follitropin receptor
  10. Target

    Muscarinic acetylcholine receptor M4

    go.drugbank.com/bio_entities/BE0000405
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M4Function: G protein-coupled acetylcholine receptor activity