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Displaying results 801 - 810 of 10000 in total
  1. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.

    Mixtures: Maux De Gorge Et De LA Toux Extra-fort, Cold & Flu-IN-oneCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist
  2. Drug

    Daratumumab

    go.drugbank.com/drugs/DB09331
    ApprovedInvestigational

    [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs.

    Products: Darzalex IV
  3. Drug

    Colistin

    go.drugbank.com/drugs/DB00803
    ApprovedInvestigational

    It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Rican Premix Powder 1,900 IU/mg, Collis Colistin 1,500,000 IU/g Water Soluble Powder
  4. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    into therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced

    Products: Isoptin Inj 2.5mg/ml, Covera-HS
  5. Indication

    Relapsed Multiple Myeloma

    go.drugbank.com/conditions/DBCOND0031510
    Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 more
    Synonyms: Multiple Myeloma in Relapse
  6. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.

    Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  7. Drug

    Caffeine

    go.drugbank.com/drugs/DB00201
    ApprovedInvestigational

    [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection. … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.

    Mixtures: Publix Super Markets Inc, Vtol LQProducts: KAFESIT 20 MG/ML IV ENJEKSIYON ICIN COZELTI ICEREN 10 FLAKON, KAFESIT 20 MG/ML IV ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET
  8. Indication

    Keratoconjunctivitis Sicca (KCS)

    go.drugbank.com/conditions/DBCOND0105777
    Drugs: Hydroxypropyl cellulose
    Synonyms: Keratoconjunctivitis sicca, in Sjögren syndrome, Keratoconjunctivitis sicca, in Sjogren's syndrome
  9. Drug

    Alemtuzumab

    go.drugbank.com/drugs/DB00087
    ApprovedInvestigational

    Alemtuzumab is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.[L43397] Alemtuzumab was approved by the FDA in 2001. … Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens.

    Products: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP)
  10. Drug

    Aluminum sulfate

    go.drugbank.com/drugs/DB11239
    Approved

    Al is found in materials used in the pharmaceutical industry, and in manufactured foodstuffs, cosmetics, and tap water. … Aluminum (Al) is ubiquitous and represents the third most common element in the Earth’s crust. It most commonly exists in a combined state with various other elements.

    Products: Rastringent II 250mg/ml