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Amediplase
go.drugbank.com/drugs/DB06679ExperimentalAmediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.
Lonaprisan
go.drugbank.com/drugs/DB16221InvestigationalLonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer).
Selamectin
go.drugbank.com/drugs/DB11459ExperimentalVet approvedIt also removes 2 types of lungworm in cats and one type of lungworm in dogs. It is distributed by Zoetis, a former Pfizer subsidiary. It is structurally related to ivermectin and milbemycin. … Selamectin is not approved for human use.
TH0318
go.drugbank.com/drugs/DB05145ExperimentalTH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the treatment of type 2 diabetes.
Milataxel
go.drugbank.com/drugs/DB12334InvestigationalMilataxel has been used in trials studying the treatment of Mesothelioma.
Birabresib
go.drugbank.com/drugs/DB15189InvestigationalBirabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Verubulin
go.drugbank.com/drugs/DB05585InvestigationalAntineoplastic; a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
Perillyl alcohol
go.drugbank.com/drugs/DB15289InvestigationalPerillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
Alfaxalone
go.drugbank.com/drugs/DB11371ExperimentalVet approvedIt is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. … Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin.
Reproxalap
go.drugbank.com/drugs/DB16688Investigational[L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.[L32990] … Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis