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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Selumetinib

    go.drugbank.com/drugs/DB11689
    ApprovedInvestigational

    NF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193608] Use of selumetinib in this population has shown efficacy in shrinking associated tumours and is linked to other positive clinical outcomes.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: KOSELUGO HARD CAPSULES 10MG, KOSELUGO HARD CAPSULES 25MG
  2. Drug

    Nintedanib

    go.drugbank.com/drugs/DB09079
    ApprovedInvestigational

    Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]

    Categories: Antineoplastic and Immunomodulating AgentsProducts: OFEV SOFT CAPSULES 150MG, OFEV SOFT CAPSULES 100MG
  3. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation semisynthetic cephalosporin. … [A262894,A263011 ,L49293] Cephalosporins are beta-lactam antibiotics and can be used to treat gram-positive and gram-negative bacterial infections which include conditions such as skin infections, resistant

    Categories: cefixime and ornidazole, cefixime and azithromycinProducts: CEFIXIMA MK 20MG/ML, hovid-Xyfisim Granules 50mg
  4. Drug

    Calcium citrate

    go.drugbank.com/drugs/DB11093
    ApprovedInvestigational

    Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.

    Mixtures: Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iu, Calcium-magnesium With K & Zn and Vitamin D3Categories: Compounds used in a research, industrial, or household setting, Diet, Food, and Nutrition
  5. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    that NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.[L11347]

    Mixtures: ATOZET TABLET 10MG/20MG, Atozet 10mg/20mg film-coated tabletsCategories: pravastatin and ezetimibe, simvastatin and ezetimibe
  6. Drug

    D-alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14002
    ApprovedNutraceuticalVet approved

    Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.

    Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Vit E 400unit W Selenium 50mcgCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household setting
  7. Drug

    Iron Dextran

    go.drugbank.com/drugs/DB00893
    ApprovedInvestigationalVet approved

    Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. … Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.

    Mixtures: Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic Acid, Se-Tan DHACategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Trihexyphenidyl

    go.drugbank.com/drugs/DB00376
    ApprovedInvestigational

    [A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects. … [L31843] It has largely been replaced by drugs such as [levodopa].[L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768]

    Products: ARTANE 5MG, PARKOPAN 5MG
  9. Drug

    Ctenocephalides felis

    go.drugbank.com/drugs/DB10693
    Approved

    Cat flea allergenic extract is used in allergenic testing.

    Synonyms: cat flea allergenic extractProducts: Cat Flea
  10. Pathway

    Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type

    smpdb.ca/view/SMP0125684
    Disease

    Symptoms include megaloblastic anemia, and can also include developmental delays, seisures and kidney failure. Treatment with vitamin B12, as well as folates and betaine is effective. … Methionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more