Search

Displaying results 811 - 820 of 10000 in total
  1. Target

    Apolipoprotein A-IV

    go.drugbank.com/bio_entities/BE0009049
    TargetHumans

    Apoa-IV is a major component of HDL and chylomicrons … May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.

    Polypeptides: Apolipoprotein A-IV
  2. Target

    HSP40, subfamily A

    go.drugbank.com/bio_entities/BE0009270
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: HSP40, subfamily ASynonyms: HSP40, subfamily A, putative
  3. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes.

    Mixtures: Fem Time Tab, Nutrilite Double XSynonyms: K
  4. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. … It is also stated that no more than 1% of the total protein should be gamma globulin.[L2260] PPFh is a sterile, frozen solution of solvent/detergent treated human plasma.

    Products: OCTAPLAS Blood Group A, Octaplas SD Blutgruppe A zur Infusion
  5. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid
  6. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    It may cause a superinfection with gram-positive organisms. … A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid
  7. Drug

    Nitazoxanide

    go.drugbank.com/drugs/DB00507
    ApprovedInvestigationalVet approved

    Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].

    Categories: Heterocyclic Compounds, 1-RingProducts: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL
  8. Drug

    Sulfasalazine

    go.drugbank.com/drugs/DB00795
    ApprovedInvestigational

    [A255582] Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability. … It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).

    Categories: Non COX-2 selective NSAIDSSynonyms: 柳氮磺吡啶, 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid
  9. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants.

    Mixtures: Cellisys EX Wrinkle Solution, Cellisys EX EGF Wrinkle 29 ActivatorCategories: Compounds used in a research, industrial, or household setting
  10. Indication

    Severe Hemophilia A

    go.drugbank.com/conditions/DBCOND0034640
    Drugs: Valoctocogene roxaparvovec
    Synonyms: Hemophilia A, Severe, Severe Hemophilia A