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Tumor necrosis factor receptor superfamily member 10B
go.drugbank.com/bio_entities/BE0003433TargetHumansReceptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor.
Polypeptides: Tumor necrosis factor receptor superfamily member 10BSynonyms: Death receptor 5, TRAIL receptor 2Tumor necrosis factor receptor superfamily member 9
go.drugbank.com/bio_entities/BE0003463TargetHumansReceptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable)
Polypeptides: Tumor necrosis factor receptor superfamily member 9Synonyms: 4-1BB ligand receptorGamma-aminobutyric acid receptor subunit gamma-3
go.drugbank.com/bio_entities/BE0003594TargetHumansGamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity). GABA-gated chloride channels, also named GABA(A) receptors (GA...
Polypeptides: Gamma-aminobutyric acid receptor subunit gamma-3Synonyms: GABA(A) receptor subunit gamma-3Acetylcholine receptor subunit alpha-type unc-38
go.drugbank.com/bio_entities/BE0004925TargetCaenorhabditis elegansAlpha subunit of nicotinic acetylcholine receptor (nAChR) (PubMed:15990870, PubMed:20027209, PubMed:9221782).
Polypeptides: Acetylcholine receptor subunit alpha-type unc-38Acetylcholine receptor subunit beta-type lev-1
go.drugbank.com/bio_entities/BE0004927TargetCaenorhabditis elegansNon-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine.
Polypeptides: Acetylcholine receptor subunit beta-type lev-1Calcitonin gene-related peptide type 1 receptor
go.drugbank.com/bio_entities/BE0009009TargetHumansG protein-coupled receptor which specificity is determined by its interaction with receptor-activity-modifying proteins (RAMPs) (PubMed:32296767, PubMed:33602864, PubMed:8626685). … Together with RAMP1, form the receptor complex for calcitonin-gene-related peptides CALCA/CGRP1 and CALCB/CGRP2 (PubMed:33602864).
Polypeptides: Calcitonin gene-related peptide type 1 receptorSynonyms: Calcitonin receptor-like receptor, CGRP type 1 receptorReceptor-interacting serine/threonine-protein kinase 1
go.drugbank.com/bio_entities/BE0009531TargetHumansSerine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways (PubMed:17703191, PubMed:24144979, PubMed:31827280, PubMed:31827281, PubMed:32657447, PubMed:35831301). Exhibits kinase act...
Polypeptides: Receptor-interacting serine/threonine-protein kinase 1Synonyms: Receptor-interacting protein 1Receptor-interacting serine/threonine-protein kinase 4
go.drugbank.com/bio_entities/BE0009533TargetHumansSerine/threonine protein kinase (By similarity). Required for embryonic skin development and correct skin homeostasis in adults, via phosphorylation of PKP1 and subsequent promotion of keratinocyte differentiation and cell adhesion (By s...
Polypeptides: Receptor-interacting serine/threonine-protein kinase 4Synonyms: Ankyrin repeat domain-containing protein 3Tyrosine-protein phosphatase non-receptor type 12
go.drugbank.com/bio_entities/BE0009940TargetHumansDephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:18559503). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2...
Polypeptides: Tyrosine-protein phosphatase non-receptor type 12Tumor necrosis factor receptor superfamily member 6
go.drugbank.com/bio_entities/BE0010463TargetHumansReceptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor.
Polypeptides: Tumor necrosis factor receptor superfamily member 6Synonyms: FASLG receptor