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Displaying results 8231 - 8240 of 10000 in total
  1. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription … [A204134,A204161] Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide functional group, with the former being largely responsible for the molecule’s lipid solubility

    Synonyms: BR1015-2Mixtures: RATEN PLUS 4 MG/1.25 MG TABLET, PERDAPAX 4 MG/1.25 MG TABLET, 30 ADET
  2. Pathway

    Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0230132
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  3. Pathway

    Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0287915
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  4. Pathway

    Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0287943
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  5. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself. … It is a derivative of 19-nortestosterone and has antiandrogenic properties.

    Synonyms: 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one, 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrileMixtures: DIENILLE 2 MG/0.03 MG FILM KAPLI TABLET ,63 TABLET, Foxinette 0,03 mg/2 mg 21+7 - Filmtabletten
  6. Drug

    Acetohydroxamic acid

    go.drugbank.com/drugs/DB00551
    ApprovedInvestigational

    Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. … It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.

    Synonyms: N-Hydroxyacetamide, N-AcetylhydroxylamineProducts: QUINOPRON ® INYECTABLE 200 MG, CIPROFLOXACINO 100 MG/10 ML INYECTABLE
  7. Drug

    Tremelimumab

    go.drugbank.com/drugs/DB11771
    ApprovedInvestigational

    Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). … CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells.

    Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet
  8. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.

    Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  9. Pathway

    Acylcarnitine (6Z)-3-Hydroxydodec-6-enoylcarnitine

    smpdb.ca/view/SMP0124013
    Metabolic

    (6Z)-3-Hydroxydodec-6-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (6Z)-3-hydroxydodec-6-enoyl-CoA reacts with L-carnitine to form (6Z)-3-hydroxydodec-6-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.

    International brands: Digocard-GCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein substrates with a Narrow Therapeutic Index