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Displaying results 821 - 830 of 6949 in total
  1. Drug

    Clofazimine

    go.drugbank.com/drugs/DB00845
    ApprovedInvestigationalWithdrawn

    Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy.

    Categories: Antiinfectives for Systemic Use, Drugs for Treatment of Lepra
  2. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD).

    Categories: NMDA Receptor Antagonists, N-methyl-D-aspartate Receptor Antagonist
  3. Drug

    Testosterone enanthate

    go.drugbank.com/drugs/DB13944
    ApprovedInvestigational

    The majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … [L8941] In 2017, about 6.5 million retail prescriptions for testosterone therapy were filled [L4659].

    Categories: Hormonal Contraceptives for Systemic Use
  4. Drug

    Anbenitamab

    go.drugbank.com/drugs/DB18411
    Investigational

    Synonyms: IMMUNOGLOBULIN G1 (369-SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS
  5. Target

    Prostacyclin receptor

    go.drugbank.com/bio_entities/BE0000475
    TargetHumans

    Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase

    Polypeptides: Prostacyclin receptorSynonyms: PGI receptor, PGI2 receptor
  6. Target

    Glucagon receptor

    go.drugbank.com/bio_entities/BE0000527
    TargetHumans

    G protein-coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis.

    Polypeptides: Glucagon receptorFunction: glucagon receptor activity
  7. Target

    Erythropoietin receptor

    go.drugbank.com/bio_entities/BE0000654
    TargetHumans

    Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed:10388848, PubMed:2163695, PubMed:2163696, PubMed:8662939, PubMed:9774108).

    Polypeptides: Erythropoietin receptorFunction: erythropoietin receptor activity
  8. Target

    Nociceptin receptor

    go.drugbank.com/bio_entities/BE0002378
    TargetHumans

    G protein-coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin.

    Polypeptides: Nociceptin receptorSynonyms: Orphanin FQ receptor, Kappa-type 3 opioid receptor
  9. Target

    Thrombopoietin receptor

    go.drugbank.com/bio_entities/BE0003440
    TargetHumans

    Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation.

    Polypeptides: Thrombopoietin receptorFunction: thrombopoietin receptor activity
  10. Target

    Poliovirus receptor

    go.drugbank.com/bio_entities/BE0004247
    TargetHumans

    Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological sy...

    Polypeptides: Poliovirus receptor