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Diphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. … Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies,
Synonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineInternational brands: Dormarex 2Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. … It is sold under several brand names, most notably Tinactin and Odor Eaters.
Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterMixtures: PERMUT®, เดอมิกซ์-4Tick-Borne Encephalitis, European
go.drugbank.com/conditions/DBCOND0144103Synonyms: Tick-Borne Encephalitis, EuropeanKynurenine--oxoglutarate transaminase 1
go.drugbank.com/bio_entities/BE0000273TargetEnzymeHumansCatalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047)
Synonyms: Cysteine-S-conjugate beta-lyaseFunction: cysteine-S-conjugate beta-lyase activityHematopoietic prostaglandin D synthase
go.drugbank.com/bio_entities/BE0001167TargetHumansBifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide rang...
Synonyms: Glutathione S-transferaseCytosolic non-specific dipeptidase
go.drugbank.com/bio_entities/BE0018303EnzymeHumansN-[(S)-lactoyl]-L-phenylalanine is an exercise-induced metabolite that influences food intake and systemic energy balance (PubMed:25964343). … Upon physiological conditions of amino acids and lactate excess can also catalyze a reverse proteolysis reaction, generating N-[(S)-lactoyl]-L-phenylalanine and possibly other N-lactoyl-amino acids which
Synonyms: HEL-S-13Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIn particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194] … Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase.
Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-X4-aminobutyrate aminotransferase GabT
go.drugbank.com/bio_entities/BE0001510TargetEscherichia coli (strain K12)Pyridoxal phosphate-dependent enzyme that catalyzes transamination between primary amines and alpha-keto acids. Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semia...
Synonyms: (S)-3-amino-2-methylpropionate transaminaseAlcohol dehydrogenase class-3
go.drugbank.com/bio_entities/BE0000009TargetEnzymeHumansAlso acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation (By similarity) … Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164).
Synonyms: S-(hydroxymethyl)glutathione dehydrogenaseMyosin regulatory light chain 12A
go.drugbank.com/bio_entities/BE0004293TargetHumansMyosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)
Synonyms: HEL-S-24