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Advanced Hormone Dependent Prostate Cancer
go.drugbank.com/conditions/DBCOND0064061Etonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. … [A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Mixtures: Etonogestrel and Ethinyl Estradiol, Etonogestrel/Ethinyl EstradiolIbutilide
go.drugbank.com/drugs/DB00308ApprovedIt is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR). … Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations.
Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity. … In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol].
Mixtures: Ophtrivin A Ophthalmic DpsCategories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsOxymetholone
go.drugbank.com/drugs/DB06412ApprovedIllicitIn 2009, no producers of oxymetholone were identified worldwide (SRI 2009), but it was available from 14 suppliers, including 8 U.S. suppliers (ChemSources 2009). … Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth
Products: HAN SEO OXYMETHOLONE TABLET 50 mgNifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigational[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].
Products: Gen Nifedipine Cap 10mg USP, NIFEDIPINO MK 10 MG. CAPSULASTrastuzumab duocarmazine
go.drugbank.com/drugs/DB16342InvestigationalTrastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsPeracetic acid
go.drugbank.com/drugs/DB14556InvestigationalIt has an acrid odor and is used as a disinfectant.
Categories: Compounds used in a research, industrial, or household settingProducts: Pu Us Pure, Pu Us LemonSphingolipid Signaling (Receptor)
smpdb.ca/view/SMP0524344SignalingThrough these receptor‑specific G protein couplings—spanning cAMP suppression, Ca²⁺ mobilization, PKC activation, Rho GTPase–driven cytoskeletal remodeling, and PI3K/Akt and MAPK pathways—S1P orchestrates
Enzymes: Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor 4