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Displaying results 841 - 850 of 10000 in total
  1. Target

    L-lactate dehydrogenase A-like 6A

    go.drugbank.com/bio_entities/BE0000297
    TargetHumans

    Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme (PubMed:18351441).

    Polypeptides: L-lactate dehydrogenase A-like 6A
  2. Target

    D-alanine--D-alanine ligase A

    go.drugbank.com/bio_entities/BE0000733
    TargetEscherichia coli (strain K12)

    Cell wall formation.

    Polypeptides: D-alanine--D-alanine ligase ASynonyms: D-Ala-D-Ala ligase A, D-alanylalanine synthetase A
  3. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0001014
    TargetHumans

    Inhibits replication of influenza A virus (IAV) (PubMed:19207730). … Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (PubMed:11943775

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Cyclophilin A
  4. Target

    Ribosomal small subunit pseudouridine synthase A

    go.drugbank.com/bio_entities/BE0001276
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.

    Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase A
  5. Target

    Methane monooxygenase component A alpha chain

    go.drugbank.com/bio_entities/BE0003331
    TargetEnzymeMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

    It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.

    Polypeptides: Methane monooxygenase component A alpha chain
  6. Target

    DNA polymerase epsilon catalytic subunit A

    go.drugbank.com/bio_entities/BE0003614
    TargetHumans

    Along with DNA polymerase POLD1 and DNA polymerase POLK, has a role in excision repair (NER) synthesis following UV irradiation (PubMed:20227374)

    Polypeptides: DNA polymerase epsilon catalytic subunit ASynonyms: DNA polymerase II subunit A
  7. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    zinc as a marker of these diseases [L2097]. … A metallic element of atomic number 30 and atomic weight 65.38.

    Mixtures: BiO-LiFE Anti-FR+Selenium Tablets, O-Cal FA multivitaminProducts: Port A Mins Super Zinc 15, Port A Mins Super Zinc 30
  8. Target

    Methylmalonic aciduria type A protein, mitochondrial

    go.drugbank.com/bio_entities/BE0000320
    TargetHumans

    Plays a dual role as both a protectase and a reactivase for MMUT (PubMed:21138732, PubMed:28943303). … Functions as a G protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) (PubMed:20876572, PubMed:28497574).

    Polypeptides: Methylmalonic aciduria type A protein, mitochondrial
  9. Target

    Ribosomal small subunit pseudouridine synthase A

    go.drugbank.com/bio_entities/BE0002034
    TargetEscherichia coli (strain K12)

    Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.

    Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase A
  10. Target

    Peroxisomal acyl-coenzyme A oxidase 1

    go.drugbank.com/bio_entities/BE0004135
    TargetEnzymeHumans

    May play a role in peroxisomal beta-oxidation step in polyunsaturated fatty acids (PUFAs) biosynthesis. … Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular

    Polypeptides: Peroxisomal acyl-coenzyme A oxidase 1