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Displaying results 8501 - 8510 of 10000 in total
  1. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol is formulated as a racemic mixture of the R- and S-isomers. … The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity.

    Mixtures: ULAX-C, UNIBRON RCategories: Adrenergic beta-2 Receptor Agonists, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Ganciclovir

    go.drugbank.com/drugs/DB01004
    ApprovedInvestigational

    An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

    Synonyms: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-oneCategories: MATE 1 Substrates, MATE 2 Substrates
  3. Drug

    Hydroxyurea

    go.drugbank.com/drugs/DB01005
    ApprovedInvestigational

    Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.

    Synonyms: N-Hydroxyurea, N-CarbamoylhydroxylamineCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  4. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: LETROLE®, LET®2.5MG
  5. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Synonyms: 2-(3-Benzoylphenyl)propionic acid, 3-Benzoyl-α-methylbenzeneacetic acidCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  6. Drug

    Edrophonium

    go.drugbank.com/drugs/DB01010
    Approved

    A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.

    Synonyms: 3-hydroxy-N,N-dimethyl-N-ethylanilinium, N-ethyl-3-hydroxy-N,N-dimethylaniliniumCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Cinacalcet

    go.drugbank.com/drugs/DB01012
    ApprovedInvestigational

    Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.

    Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Synonyms: Clobetasol propionate E, 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionateInternational brands: Embeline E
  9. Drug

    Balsalazide

    go.drugbank.com/drugs/DB01014
    Approved

    The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. … Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA.

    Synonyms: (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid, (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acidCategories: Non COX-2 selective NSAIDS
  10. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    [A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.

    Synonyms: 7-Dimethylamino-6-demethyl-6-deoxytetracycline, (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamideProducts: PERIOCLINE PERIODONTAL OINTMENT 2% W/W, XELTETRA-M