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GTP-binding protein Rheb
go.drugbank.com/bio_entities/BE0004594TargetHumansIn response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1 (PubMed:24529379, PubMed:33157014). Has low intrinsic GTPase activity (PubMed:15340059) … In response to nutrients, growth factors or amino acids, specifically activates the protein kinase activity of MTOR, the catalytic component of the mTORC1 complex: acts by causing a conformational change
Synonyms: Ras homolog enriched in brainClarithromycin
go.drugbank.com/drugs/DB01211ApprovedInvestigationalClarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
Products: KLARICID®IV, KLACID IV FOR INJECTION 500 mg/vialMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approved[A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Products: BIENEX INY®, EXEN 15 MG/1.5 ML IM ENJEKSİYONLUK ÇÖZELTİ, 3 AMPULLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalLatanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].
Mixtures: Fixapost 50 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisCategories: Compounds used in a research, industrial, or household settingSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigational[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.
Synonyms: (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamideProducts: Imitrex Inj 12mg/ml, SUMATRIPTAN-HEXAL N 50MGIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational[L41780] Ioversol was approved by the FDA in 1989 and is currently indicated for computed tomographic (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamideHuntington's Disease (HD)
go.drugbank.com/conditions/DBCOND0053941Synonyms: [X]Dementia in Huntington's disease (disorder)Amino acids
go.drugbank.com/drugs/DB09393InvestigationalMixture of amino acids ; used for parenteral nutrition in infants.
Mixtures: Ari S-LinerProducts: AMINOSTERIL N-HEPA, AMINOPLASMAL HEPA %10 IV İNFÜZYON SOLÜSYONU, 500 MLSilver cation
go.drugbank.com/drugs/DB14521InvestigationalMixtures: Silver Ion Antibacterial Gel, Ancos Silver Ion Hand SanitizerSynonyms: Silver, ion (Ag1+)