NCT05773196
Prospective Single-Timepoint Huntington's Disease Biospecimen Collection Study No drug interventions Not Available Not Available recruiting NCT03724136
Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study No drug interventions treatment Not Available enrolling_by_invitation NCT05475483
Efficacy and Safety on SOM3355 in Huntington's Disease Chorea treatment 2 active_not_recruiting NCT03761849
A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease treatment 3 completed NCT04000594
A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's Disease treatment 1 completed NCT03575676
Efficacy and Safety of SOM3355 in Huntington's Disease Chorea No drug interventions treatment 2 completed NCT01412151
Creatine Safety & Tolerability in Huntington's Disease treatment 2 completed NCT04102579
Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease treatment 3 completed NCT04400331
Open-Label Rollover Study for Continuing Valbenazine Administration for the Treatment of Chorea Associated With Huntington Disease treatment 3 active_not_recruiting NCT06312189
Long-term Study to Evaluate Safety and Tolerability of Valbenazine in Participants With Chorea Associated With Huntington Disease in Canada treatment 3 enrolling_by_invitation NCT00465790
Research of Biomarkers in Parkinson Disease No drug interventions Not Available Not Available completed NCT00277602
Riluzole in Huntington's Disease treatment 3 completed NCT04917133
Adapted Physical Activity Effect on Abilities and Quality of Life of Huntington Patients and Relatives During Rehab Stay No drug interventions supportive_care Not Available completed NCT01554033
Study of Huntington Patients in Connection With European Huntington's Disease Network (EHDN) No drug interventions Not Available Not Available unknown_status NCT05225051
N- Homocysteinylated Huntingtin in Huntington's Disease No drug interventions basic_science Not Available unknown_status NCT05326451
Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease No drug interventions treatment Not Available recruiting NCT05686551
GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease. treatment 2 recruiting NCT05509153
A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers treatment 2 not_yet_recruiting NCT04617847
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease treatment 1 / 2 terminated NCT00788047
A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan basic_science 1 completed NCT02453061
A Comparative Phase 2 Study Assessing the Efficacy of Triheptanoin, an Anaplerotic Therapy in Huntington's Disease treatment 2 completed NCT04012411
Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's Disease No drug interventions basic_science Not Available recruiting NCT01834911
Effect of Tetrabenazine on Stroop Interference in HD treatment 4 completed NCT02464293
A Pilot Evaluation of Mindfulness-based Cognitive Therapy for People With Huntington's Disease No drug interventions treatment Not Available completed NCT06546488
Cognitive Assessment Tools for Huntington's Disease. No drug interventions Not Available Not Available not_yet_recruiting NCT04556656
PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD treatment 3 active_not_recruiting NCT02728115
Safety Evaluation of Cellavita HD Administered Intravenously in Participants With Huntington's Disease No drug interventions other 1 active_not_recruiting NCT06209515
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study No drug interventions Not Available Not Available active_not_recruiting NCT01485952
An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196 No drug interventions treatment 1 completed NCT02819700
Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI) No drug interventions Not Available Not Available completed NCT02727270
Measuring Cortisol Levels in Persons With Parkinson's (PD) No drug interventions Not Available Not Available completed NCT01458470
A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease treatment 2 completed NCT00831506
Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects treatment 1 completed NCT06194006
Long Term Follow-up Grafted Huntington's Disease Patients No drug interventions other Not Available not_yet_recruiting NCT04406636
Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD No drug interventions Not Available Not Available unknown_status NCT04257513
Clinical Study to Monitor Plasma Levels of 24OHC in Subject With HD No drug interventions Not Available Not Available unknown_status NCT02563418
Feasibility of a Video-oculography in Patients With Huntington's Disease VOG-HD Study No drug interventions diagnostic Not Available unknown_status NCT06391619
Huntington's Disease Young Adult Study 2.0 No drug interventions Not Available Not Available active_not_recruiting NCT02994719
Gait Analysis in Neurological Disease Not Available Not Available recruiting NCT03854019
Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease treatment 3 completed NCT01573819
A Repeat Dose Study in Healthy Volunteers Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK356278 basic_science 1 completed NCT03142217
Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria No drug interventions other Not Available withdrawn NCT02268617
Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease No drug interventions treatment Not Available completed NCT05243017
Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease No drug interventions treatment 1 / 2 recruiting NCT05358717
A Study to Evaluate the Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD) No drug interventions treatment 2 recruiting NCT04478734
Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease treatment 2 recruiting NCT05032196
Study of WVE-003 in Patients With Huntington's Disease treatment 1 / 2 completed NCT03252535
Dose-response Evaluation of the Cellavita HD Product in Patients With Huntington's Disease No drug interventions treatment 2 completed NCT04071639
Symptomatic Therapy for Patients With Huntington's Disease treatment 1 recruiting NCT03034122
Is Caffeine an Environmental Modifier in Huntington's Disease? No drug interventions Not Available Not Available recruiting NCT04925622
Complex Eye Movements in Parkinson's Disease and Related Movement Disorders No drug interventions Not Available Not Available completed NCT06024265
The Safety and Tolerability Study With ER2001 Intravenous Injection in Adults With Early Manifest Huntington's Disease treatment 0 recruiting NCT01359774
31P-MRS and Huntington Disease No drug interventions prevention Not Available completed NCT00870974
A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions Not Available 1 completed NCT04589182
Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease No drug interventions treatment Not Available unknown_status NCT03709173
FuRST 2.0 Cognitive Pre-testing - Round 2 No drug interventions Not Available Not Available completed NCT05541627
A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's Disease No drug interventions treatment 1 / 2 active_not_recruiting NCT03421327
Genetic Risk: Whether, When, and How to Tell Adolescents No drug interventions Not Available Not Available completed NCT04818060
Preparing for Prevention of Huntington's Disease (PREVENT-HD) No drug interventions Not Available Not Available recruiting NCT02907294
Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers No drug interventions treatment 1 terminated NCT04701580
Synaptic Density and Progression of Huntington's Disease. No drug interventions diagnostic Not Available completed NCT06097780
Efficacy and Safety of NestaCell® in Huntington's Disease No drug interventions treatment 3 not_yet_recruiting NCT01306929
Open-label Extension Study of Pridopidine (ACR16) in the Symptomatic Treatment of Huntington Disease treatment 2 completed NCT01590589
REGISTRY - an Observational Study of the European Huntington's Disease Network (EHDN) No drug interventions Not Available Not Available completed NCT04826692
TEsting METformin Against Cognitive Decline in HD treatment 3 unknown_status NCT05828992
Benchmarking Integrated Care for People Living With Huntington's Disease in England No drug interventions Not Available Not Available recruiting NCT03713892
CKD-504 in SAD and MAD in Healthy Korean and Caucasian Adult Male and Female Subjects treatment 1 unknown_status NCT02218567
Behavioural Problems in Huntington Disease : Analysis and Enhancement of Caregiver and Patient Experience No drug interventions supportive_care Not Available terminated NCT06414967
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD) No drug interventions supportive_care Not Available recruiting NCT05238701
A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects No drug interventions treatment 1 completed NCT04270604
Biological Sample Collection for Research and Biobanking No drug interventions Not Available Not Available terminated NCT06539169
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases No drug interventions Not Available Not Available recruiting NCT06448546
Gut Microbiomes in HD No drug interventions Not Available Not Available not_yet_recruiting NCT03119246
Beta Testing of a New Assessment in Huntington's Disease (HD) No drug interventions other Not Available unknown_status NCT03052712
Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies No drug interventions diagnostic Not Available terminated NCT00313495
Cooperative Huntington's Observational Research Trial No drug interventions Not Available Not Available unknown_status NCT04885114
Safety and Tolerability Study With VY-HTT01, in Adults With Early Manifesting Huntington's Disease No drug interventions treatment 1 withdrawn NCT06147414
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders No drug interventions Not Available Not Available not_yet_recruiting NCT00190450
MIG-HD: Multicentric Intracerebral Grafting in Huntington's Disease No drug interventions treatment 2 completed NCT04515550
Mitochondrial Biomarkers in Huntington's Disease No drug interventions Not Available Not Available completed NCT05250323
Energy Balance in Huntington's Disease. A Multidisciplinary Study Approach for a Complex Problem (BEHD-EM) No drug interventions Not Available Not Available completed NCT01937923
A Pre-Cellular Therapy Observational Study in Early Huntington's Disease No drug interventions Not Available Not Available completed NCT05822908
A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD treatment 1 / 2 recruiting NCT03980938
Within Subject Crossover Study of Cognitive Effects of Neflamapimod in Early-Stage Huntington Disease treatment 2 terminated NCT00052143
Prospective Huntington At Risk Observational Study No drug interventions Not Available Not Available completed NCT05358821
28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease No drug interventions treatment 2 completed NCT02535884
Deep Brain Stimulation (DBS) of the Globus Pallidus (GP) in Huntington's Disease (HD) No drug interventions treatment Not Available completed NCT04231487
Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders No drug interventions Not Available Not Available unknown_status NCT02336633
Resveratrol and Huntington Disease No drug interventions treatment Not Available completed NCT05913154
Impact of Apathy on Caregiving in HD. Version 1 No drug interventions Not Available Not Available enrolling_by_invitation NCT05943054
Striatum and Hippocampus on Different Time Scales No drug interventions other Not Available recruiting NCT06216054
Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects No drug interventions treatment 1 recruiting NCT04698551
NIPD on cffDNA for Triplet Repeat Diseases No drug interventions Not Available Not Available unknown_status NCT06469853
Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients No drug interventions treatment 2 recruiting NCT01834053
Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea. No drug interventions treatment 1 / 2 unknown_status NCT03886753
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products No drug interventions Not Available Not Available terminated NCT05808153
Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression No drug interventions other Not Available recruiting NCT00675077
Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD) No drug interventions treatment 1 unknown_status NCT00539747
Making Sense of a Positive Genetic Test Result for Huntington Disease No drug interventions Not Available Not Available completed NCT00632645
Neuroleptic and Huntington Disease Comparison of : Olanzapine, la Tetrabenazine and Tiapride treatment 3 completed NCT06475898
Longitudinal Endpoint Assessment of Disease Burden in HD No drug interventions Not Available Not Available recruiting NCT03810898
iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [¹¹C]CHDI-00485180-R and [¹¹C]CHDI-00485626 No drug interventions other 0 terminated NCT03417583
Assessing Efficacy of Neuropsychiatric Assessment and Treatment Protocols in Huntington's Disease Patients No drug interventions other Not Available completed NCT00146211
TREND-HD - A Trial of Ethyl-EPA (Miraxion™) in Treating Mild to Moderate Huntington's Disease treatment 3 completed NCT01590888
Effect of PBT2 in Patients With Early to Mid Stage Huntington Disease No drug interventions treatment 2 completed NCT05748288
Development of the Virtual Unified Huntington's Disease Rating Scale No drug interventions Not Available Not Available completed NCT03764215
Nilotinib in Huntington's Disease treatment 1 unknown_status NCT05224115
Dosimetry of [11C]CHDI-180R and [11C]CHDI-626. No drug interventions Not Available Not Available completed NCT06585332
Handgrip and Respiratory Dysfunction in HD Patients. No drug interventions Not Available Not Available recruiting NCT01602900
Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease treatment 1 completed NCT04370470
Development of Assessments for Later Stage HD No drug interventions Not Available Not Available unknown_status NCT03193099
Decoding Presymptomatic White Matter Changes in Huntington Disease No drug interventions other Not Available completed NCT06203106
NYSCF Scientific Discovery Biobank No drug interventions Not Available Not Available recruiting NCT00368849
Atomoxetine and Huntington's Disease treatment 2 completed NCT03515213
Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease treatment 2 completed NCT06082713
Extracellular Vesicles for HD No drug interventions Not Available Not Available recruiting NCT04244513
Deep Brain Stimulation Treatment for Chorea in Huntington's Disease No drug interventions treatment Not Available unknown_status NCT01842919
Dance and Huntington Disease No drug interventions other Not Available completed NCT04219241
Clinical Extension Study for Safety and Efficacy Evaluation of Cellavita-HD Administration in Huntington's Patients. No drug interventions treatment 2 / 3 active_not_recruiting NCT06444217
Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD No drug interventions basic_science Not Available not_yet_recruiting NCT01919034
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients No drug interventions Not Available Not Available completed NCT04201834
Risperidone for the Treatment of Huntington's Disease Involuntary Movements treatment 2 completed NCT00051324
Neurobiological Predictors of Huntington's Disease (PREDICT-HD) No drug interventions Not Available Not Available active_not_recruiting NCT00988624
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine) Not Available 1 completed NCT00271596
Citalopram to Enhance Cognition in HD treatment 2 completed NCT03787758
A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of SAGE-718 Oral Solution in Patients With Huntington's Disease - Part B No drug interventions treatment 1 completed NCT00654563
Memory Disorders Registry No drug interventions Not Available Not Available completed NCT05534139
Clinicopathological MRI and CSF Correlates in Huntington's Disease. No drug interventions Not Available Not Available unknown_status NCT04421339
Melatonin for Huntington's Disease (HD) Gene Carriers With HD Related Sleep Disturbance - a Pilot Study No drug interventions treatment Not Available completed NCT01412125
Study of Biomarkers That Predict the Evolution of Huntington's Disease No drug interventions Not Available Not Available unknown_status NCT04429230
Non-invasive Brain Stimulation in Huntington's Disease No drug interventions treatment Not Available unknown_status NCT01339130
Assessment of Social-emotional Functioning in Neurological Diseases No drug interventions diagnostic Not Available completed NCT03434548
iMarkHD: In Vivo Longitudinal Imaging of HD Pathology No drug interventions Not Available Not Available recruiting NCT00724048
A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's Disease treatment 2 completed NCT04301726
Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated With HD treatment 1 unknown_status NCT01085266
An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease treatment 3 terminated NCT04630574
Characterization and Quantification of Motor Speech Disorders in Huntington's Disease: Identification of Acoustic Markers No drug interventions Not Available Not Available completed NCT00514774
Ursodiol in Huntington's Disease treatment 1 unknown_status NCT05157074
Group Drum-Based Music Therapy Intervention for Parkinson's Disease/Huntington's Disease No drug interventions treatment Not Available completed NCT05668520
A Pilot Study of Nutritional Status in Patients With Huntington's Disease No drug interventions Not Available Not Available enrolling_by_invitation NCT06343220
Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research No drug interventions Not Available Not Available recruiting NCT04713982
Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease treatment 2 / 3 recruiting NCT06254482
An Extension Study to Evaluate the Long-Term Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD) No drug interventions treatment 2 enrolling_by_invitation NCT05360082
Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD. No drug interventions Not Available Not Available not_yet_recruiting NCT03296176
Metabolomic Study in Huntington's Disease (METABO-HD) No drug interventions other Not Available unknown_status NCT03599076
Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease Huntington's Disease No drug interventions Not Available Not Available unknown_status NCT04617860
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease treatment 1 / 2 terminated NCT00980694
Bioavailability of Ubiquinol in Huntington Disease No drug interventions Not Available 1 completed NCT01882062
Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington Disease treatment 2 completed NCT05126862
Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3) No drug interventions treatment Not Available completed NCT00970229
Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. No drug interventions diagnostic 1 completed NCT05268029
Making HD Voices Heard No drug interventions Not Available Not Available completed NCT00075140
Family Health After Predictive Huntington Disease (HD) Testing No drug interventions Not Available Not Available completed NCT06490367
Time-Restricted Eating in Huntington's Disease: A Clinical Pilot Study No drug interventions treatment Not Available recruiting NCT04394767
Couple and Spouse Caregiver in Huntington's Disease No drug interventions Not Available Not Available recruiting NCT04514367
An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease treatment 2 completed NCT03344601
PHysical Activity and Exercise Outcomes in Huntington's Disease No drug interventions health_services_research Not Available unknown_status NCT02814201
Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm No drug interventions Not Available Not Available completed NCT05769972
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders No drug interventions treatment Not Available active_not_recruiting NCT03842969
An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies treatment 3 completed NCT03233646
Retinal Imaging in Neurodegenerative Disease No drug interventions Not Available Not Available recruiting NCT00920946
A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease treatment 3 completed NCT01357681
Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study) No drug interventions treatment 2 completed NCT05270681
Move to Improve: Telehealth Exercise to Music for HD No drug interventions treatment Not Available recruiting NCT01884181
Accelerated Diffusion MRI for Diagnosis of Hungtington Disease No drug interventions Not Available Not Available completed NCT00592995
Creatine Safety and Tolerability in Premanifest HD: PRECREST No drug interventions treatment 2 completed NCT00277355
Pilot Study of Minocycline in Huntington's Disease treatment 2 / 3 completed NCT06474650
Effect of Food on the Pharmacokinetics of LPM3770164 Sustained-release Tablets No drug interventions treatment 1 not_yet_recruiting NCT01696708
Utilization of 31P-Nuclear Magnetic Resonance Spectroscopy to Monitor Brain Energy Deficit in Huntington Disease No drug interventions basic_science Not Available completed NCT00824590
A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function treatment 1 completed NCT03225833
Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease treatment 1 / 2 terminated NCT00004753
Long-Term Study of Cerebral Glucose Metabolism in Huntington's Disease No drug interventions Not Available Not Available completed NCT03342053
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139) treatment 2 completed NCT02551705
Functional Imaging of Social Cognition in Premanifest Huntington's Disease No drug interventions basic_science Not Available unknown_status NCT05107128
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD) No drug interventions treatment 2 active_not_recruiting NCT01521832
Escalating Dose Study in Healthy Volunteers With SEN0014196 No drug interventions treatment 1 completed NCT01592552
A Biospecimen and Clinical Data Study on Patients for Drug & Biomarker Discovery No drug interventions Not Available Not Available completed NCT00491842
Individuals Patterns of Disclosure About Huntington s Disease (HD) and the Association With Adaptation to HD No drug interventions Not Available Not Available completed NCT00920699
Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL) treatment 2 completed NCT02215616
A Clinical Study in Participants With Huntington's Disease (HD) to Assess Efficacy and Safety of Three Oral Doses of Laquinimod treatment 2 completed NCT01806896
Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease treatment 2 completed NCT01860339
Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease No drug interventions Not Available Not Available recruiting NCT00001930
Treatment of Huntington's Chorea With Amantadine treatment 2 completed NCT02342548
Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 treatment 2 terminated NCT00652457
Study of Memantine to Treat Huntington's Disease treatment 4 completed NCT02481674
A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi treatment 2 completed NCT00029874
Minocycline in Patients With Huntington's Disease treatment 1 / 2 completed NCT05655520
A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease No drug interventions treatment 3 recruiting NCT02926820
Working Memory Training in Huntington's Disease No drug interventions treatment Not Available completed NCT00931073
A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers Not Available 1 completed NCT02990676
Exploring Computerised Cognitive Training for People With Huntington's Disease No drug interventions basic_science Not Available completed NCT02855476
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease No drug interventions Not Available Not Available recruiting NCT02231580
Study Exploring Safety, Pharmacokinetic and Pharmacodynamic of BN82451 in Male Huntington's Disease Patients No drug interventions treatment 2 terminated NCT00902889
Deep Brain Stimulation of the Globus Pallidus in Huntington's Disease No drug interventions treatment 1 completed NCT01879267
Exercise Effects in Huntington's Disease No drug interventions treatment Not Available completed NCT00219804
Efficacy and Safety of Tetrabenazine in Chorea No drug interventions Not Available 3 completed NCT03664804
Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease No drug interventions other 1 completed NCT03225846
Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease treatment 1 / 2 terminated NCT00975481
A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users Not Available 1 completed NCT00608881
Coenzyme Q10 in Huntington's Disease (HD) treatment 3 terminated NCT00095355
Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's Disease treatment 2 completed NCT01411150
Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study treatment 2 completed NCT00665223
A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's Disease treatment 3 completed NCT02507284
Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease treatment 2 completed NCT00825084
A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects treatment 1 completed NCT01574053
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort No drug interventions Not Available Not Available recruiting NCT01290861
Cognitive Assessment Battery (CAB) Beta Study No drug interventions Not Available Not Available completed NCT02509793
A Pilot Study Assessing Impulsivity in Patients With Huntington's Disease on Xenazine (Tetrabenazine) treatment 4 unknown_status NCT04120493
Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease No drug interventions treatment 1 / 2 recruiting NCT02494778
A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's Disease treatment 2 terminated NCT03306888
Feasibility and Acceptability of Implementing a Clinic-based Physical Activity Coaching Intervention in People With Premanifest and Early Stage HD No drug interventions other 1 / 2 completed NCT00026988
Creatine Therapy for Huntington's Disease treatment 1 / 2 completed NCT00670709
Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's Disease No drug interventions Not Available Not Available completed NCT01521585
A Phase II Safety and Tolerability Study With SEN0014196 No drug interventions treatment 2 completed NCT00497159
A Study of the Novel Drug Dimebon in Patients With Huntington's Disease treatment 2 completed NCT02550275
Social Cognition in Huntington's Disease: Cognitive Study and Functional and Morphological Imaging No drug interventions prevention Not Available completed NCT00387270
Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease treatment 1 / 2 completed NCT06585449
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease No drug interventions treatment 1 not_yet_recruiting NCT02519036
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease No drug interventions treatment 1 / 2 completed NCT00990613
A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin Not Available 1 completed NCT00827034
A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects treatment 1 completed NCT02208934
Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers No drug interventions treatment 1 completed NCT00212316
Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD) treatment 2 completed NCT03628235
HD-Charge: Indirect and Out-of-Pocket Costs of Huntington's Disease in the United States No drug interventions Not Available Not Available completed NCT01451463
Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease No drug interventions Not Available Not Available completed NCT01411163
Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability treatment 2 completed NCT02061722
[PETDE10] Imaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET. No drug interventions diagnostic 0 completed NCT02197130
Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease treatment 2 completed NCT02263430
PINS Stimulator System for Deep Brain Stimulation in Huntington's Disease No drug interventions treatment Not Available unknown_status NCT02956148
Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers No drug interventions diagnostic 0 completed NCT02101957
Multicentric Trial of the Treatment of Huntington's Disease by Cysteamine (RP103) No drug interventions treatment 2 / 3 unknown_status NCT00712426
Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) treatment 3 terminated NCT01914965
Apathy Cure Through Bupropion in Huntington's Disease treatment 2 completed NCT01485965
A Open-label Food Effect Study With SEN0014196 in Subjects With Huntington Disease No drug interventions treatment 1 completed NCT02216474
Brain Stimulation in Movement Disorders No drug interventions other Not Available completed NCT02750982
Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases. No drug interventions health_services_research Not Available completed NCT02881931
FuRST 2.0 Cognitive Pre-Testing No drug interventions Not Available Not Available completed NCT01019473
Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea treatment 2 terminated NCT00178360
Effects of Music Therapy on Huntington's Disease No drug interventions Not Available 1 completed NCT02252380
ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders No drug interventions treatment Not Available active_not_recruiting NCT01931644
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions No drug interventions Not Available Not Available completed NCT02006472
A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's Disease treatment 2 completed NCT01502046
Neuroprotection by Cannabinoids in Huntington's Disease treatment 2 completed NCT02418546
Electronic-health Application To Measure Outcomes REmotely Clinical Trial No drug interventions supportive_care Not Available completed NCT02074410
Safety and Efficacy of OMS643762 in Subjects With Huntington's Disease treatment 2 terminated NCT01735981
The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease No drug interventions treatment Not Available completed NCT00907595
Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon treatment Not Available withdrawn NCT01897896
Alternatives for Reducing Chorea in Huntington Disease treatment 3 completed