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Displaying results 861 - 870 of 8696 in total

Drug
Mometasone furoate
go.drugbank.com/drugs/DB14512
ApprovedInvestigationalVet approved
It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906]. … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295].
Mixtures: M-FURO MANT % 0.1 + % 1 KREM, 20GCategories: Corticosteroids for inhalation use, Drugs for Obstructive Airway Diseases
Drug
Sertraline
go.drugbank.com/drugs/DB01104
ApprovedInvestigational
Several weeks of therapy with sertraline may be required before beneficial effects are noticed.
Categories: Antidepressive Agents Indicated for Depression, P-glycoprotein inhibitorsProducts: Mar-sertraline, Ran-sertraline
Drug
Tucatinib
go.drugbank.com/drugs/DB11652
ApprovedInvestigational
Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer. … [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not responded adequately to other chemotherapy regimens.[L12945]
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
Drug
Lamivudine
go.drugbank.com/drugs/DB00709
ApprovedInvestigational
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Mixtures: Triumeq PD, LAMIVUDIN/ZID PUR 150/300Categories: P-glycoprotein substrates, Antivirals for Systemic Use
Drug
Lintuzumab satetraxetan AC-225
go.drugbank.com/drugs/DB15053
Investigational
Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Synonyms: HUM-195 AC-225
Drug
Coal tar
go.drugbank.com/drugs/DB11082
Approved
It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema.
Mixtures: P&s Plus, Medi-dan ShampooProducts: Pc-tar
Drug
Tryptophan
go.drugbank.com/drugs/DB00150
ApprovedInvestigationalNutraceuticalWithdrawn
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. … It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.
Mixtures: Aminosyn-PF, Aminosyn-PF
Target
Proto-oncogene Mas
go.drugbank.com/bio_entities/BE0012496
TargetHumans
Acts as functional receptor for CXCL17 and induces chemotactic movement (PubMed:41167449) … Receptor mainly stimulated by angiotensin 1-7, which is a bioactive metabolite of the angiotensin produced by ACE2 (PubMed:17984366).
Polypeptides: Proto-oncogene MasSynonyms: MAS
Drug
Ciprofloxacin
go.drugbank.com/drugs/DB00537
ApprovedInvestigational
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Mar-ciprofloxacin, Ciproflo 2mg/ml solution for IV Infusion
Drug
Vitamin E
go.drugbank.com/drugs/DB00163
ApprovedInvestigationalNutraceuticalVet approved
In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage[A176104].
Mixtures: Doctor's Choice Brand for Men, Multivitamins and Minerals for MenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers