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Displaying results 8761 - 8770 of 10000 in total
  1. Target

    3-hydroxyisobutyrate dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0000128
    TargetHumans

    Polypeptides: 3-hydroxyisobutyrate dehydrogenase, mitochondrialFunction: 3-hydroxyisobutyrate dehydrogenase activity
  2. Target

    Nitric oxide synthase 3

    go.drugbank.com/bio_entities/BE0000263
    TargetEnzymeHumans

    Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed:1378832). NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coron...

    Polypeptides: Nitric oxide synthase 3
  3. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate in glycolysis and the reverse reaction in gluconeogenesis (PubMed:11724794, PubMed:3170585). … Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their

    Polypeptides: Glyceraldehyde-3-phosphate dehydrogenase
  4. Target

    CCN family member 3

    go.drugbank.com/bio_entities/BE0001147
    TargetHumans

    Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival (PubMed:12050162, PubMed:12695522, PubMed:15181016, PubMed:15611078, PubMed:21344378). Acts b...

    Polypeptides: CCN family member 3Synonyms: Cellular communication network factor 3
  5. Target

    5'(3')-deoxyribonucleotidase, mitochondrial

    go.drugbank.com/bio_entities/BE0001515
    TargetHumans

    Dephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).

    Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: 5',3'-nucleotidase, mitochondrial, dNT-2
  6. Target

    Gentamicin 3-N-acetyltransferase

    go.drugbank.com/bio_entities/BE0001953
    TargetPseudomonas aeruginosa

    Responsible for gentamicin resistance and has a limited substrate range.

    Polypeptides: Gentamicin 3-N-acetyltransferaseSynonyms: AAC(3)-I, Aminoglycoside N(3)-acetyltransferase I
  7. Target

    Laminin subunit alpha-3

    go.drugbank.com/bio_entities/BE0002111
    TargetEnzymeHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components

    Polypeptides: Laminin subunit alpha-3
  8. Target

    Carbapenam-3-carboxylate synthase

    go.drugbank.com/bio_entities/BE0002807
    TargetErwinia carotovora

    Involved in the biosynthesis of carbapenam-3-carboxylate, a beta-lactam antibiotic of the carbapenem class. … Catalyzes the ATP-dependent formation of (3S,5S)-carbapenam-3-carboxylate from (2S,5S)-5-carboxymethylproline.

    Polypeptides: Carbapenam-3-carboxylate synthaseSynonyms: Carbapenam-3-carboxylate ligase
  9. Target

    3-hydroxyanthranilate 3,4-dioxygenase

    go.drugbank.com/bio_entities/BE0003333
    TargetRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)

    Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

    Polypeptides: 3-hydroxyanthranilate 3,4-dioxygenaseSynonyms: 3-HAO, 3-hydroxyanthranilate oxygenase
  10. Target

    Serum paraoxonase/lactonase 3

    go.drugbank.com/bio_entities/BE0003562
    EnzymeHumans

    Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic...

    Polypeptides: Serum paraoxonase/lactonase 3