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Displaying results 881 - 890 of 10000 in total
  1. Target

    Endoglucanase A

    go.drugbank.com/bio_entities/BE0002017
    TargetClostridium thermocellum

    This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Polypeptides: Endoglucanase ASynonyms: Cellulase A
  2. Target

    Pepsin A

    go.drugbank.com/bio_entities/BE0004062
    TargetSIV-mac

    Polypeptides: Pepsin A
  3. Target

    Arylsulfatase A

    go.drugbank.com/bio_entities/BE0003195
    TargetEnzymeHumans

    Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein

    Polypeptides: Arylsulfatase A
  4. Target

    Bontoxilysin-A

    go.drugbank.com/bio_entities/BE0004102
    TargetClostridium botulinum

    Polypeptides: Bontoxilysin-ASynonyms: A, boNT/A
  5. Target

    Filamin-A

    go.drugbank.com/bio_entities/BE0009099
    TargetHumans

    Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.

    Polypeptides: Filamin-ASynonyms: FLN-A
  6. Target

    Toxin A

    go.drugbank.com/bio_entities/BE0010938
    TargetPeptoclostridium difficile

    Toxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains

    Polypeptides: Toxin A
  7. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559] … Magnesium is classified as an alkaline earth metal and has 2 hydration shells.

    Mixtures: One A Day Tab, Extra Once A DayProducts: EMGE 300MG PULV Z.HER E LO, MAGNEROT A 500 BEUTEL
  8. Indication

    Severe Hemophilia A

    go.drugbank.com/conditions/DBCOND0034640
    Drugs: Valoctocogene roxaparvovec
    Synonyms: Hemophilia A, Severe, Severe Hemophilia A
  9. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N,N'-Bis(2-chloroethyl)-N-nitrosourea
  10. Drug

    Stearic acid

    go.drugbank.com/drugs/DB03193
    Approved

    It is a waxy solid.

    Mixtures: Huile D'onagre Vitamin E, O Hui Veil Fit Dual Foundation 20Synonyms: n-octadecanoic acid, C18:0