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Displaying results 881 - 890 of 10000 in total
  1. Drug

    Esmolol

    go.drugbank.com/drugs/DB00187
    ApprovedInvestigationalWithdrawn

    Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. … It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses.

    Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester
  2. Target

    Chitinase A

    go.drugbank.com/bio_entities/BE0001649
    TargetSerratia marcescens

    Polypeptides: Chitinase A
  3. Target

    Gyrase A

    go.drugbank.com/bio_entities/BE0008384
    TargetMycobacterium tuberculosis

    Polypeptides: Gyrase A
  4. Target

    Cyclin A

    go.drugbank.com/bio_entities/BE0009669
    Target

  5. Target

    Proenkephalin-A

    go.drugbank.com/bio_entities/BE0010659
    TargetHumans

    They play a role in a number of physiologic functions, including pain perception and responses to stress

    Polypeptides: Proenkephalin-A
  6. Drug

    Nitroglycerin

    go.drugbank.com/drugs/DB00727
    ApprovedInvestigational

    Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.

    Mixtures: Nitroglycerin In 5% Dextrose Inj.-400mcg/ml, Nitroglycerin In 5% Dextrose Inj.-200mcg/mlCategories: Compounds used in a research, industrial, or household setting, Vasodilators Used in Cardiac Diseases
  7. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. … It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.

    Mixtures: MEODEX®, MEODEX®Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  8. Target

    Apolipoprotein(a)

    go.drugbank.com/bio_entities/BE0001283
    TargetHumans

    Lp(a) may be a ligand for megalin/Gp 330 … Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.

    Polypeptides: Apolipoprotein(a)Synonyms: Lp(a), Apo(a)
  9. Target

    Exotoxin A

    go.drugbank.com/bio_entities/BE0001869
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38 (PubMed:21135177).

    Polypeptides: Exotoxin A
  10. Target

    Endoglucanase A

    go.drugbank.com/bio_entities/BE0002017
    TargetClostridium thermocellum

    This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Polypeptides: Endoglucanase ASynonyms: Cellulase A