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Rofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. … The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids.
Categories: COX-2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanoneGuanidine
go.drugbank.com/drugs/DB00536ApprovedA strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. … (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Categories: MATE 1 Substrates, MATE 2 SubstratesCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigationalCiprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.
Mixtures: OTOFAST®, OQ-CORT®Categories: 4-Quinolones, MATE 1 InhibitorsGadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Categories: Compounds used in a research, industrial, or household settingNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA).
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineAmoxapine
go.drugbank.com/drugs/DB00543ApprovedSee toxicity section below for a complete listing of side effects. … Amoxapine, the <i>N</i>-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines.
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepinePerflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalPerflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane
Mixtures: Optison Perflutren Protein-Type A MicrospheresCategories: Compounds used in a research, industrial, or household settingSuccimer
go.drugbank.com/drugs/DB00566ApprovedInvestigationalA mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Categories: Compounds used in a research, industrial, or household settingSynonyms: DMS-A, DIM-SAVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigational(Merck, 11th ed.)
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, BSEP/ABCB11 Substrates with a Narrow Therapeutic IndexProducts: VINBLASTINA10 MG X 1 FCO., VINKO 1 MG/ML IV INFÜZYON ICIN COZELTİ ICEREN FLAKON, 1 ADETCarbenicillin
go.drugbank.com/drugs/DB00578ApprovedBroad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Synonyms: N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid, (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCategories: Penicillin G, Heterocyclic Compounds, 2-Ring