Search
Actin-related protein 3
go.drugbank.com/bio_entities/BE0004251TargetHumansThe Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076). … ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076).
Polypeptides: Actin-related protein 3Synonyms: Actin-like protein 3Penicillin-binding protein 3
go.drugbank.com/bio_entities/BE0004654TargetStaphylococcus aureus (strain USA300)Polypeptides: Penicillin-binding protein 3Sodium bicarbonate cotransporter 3
go.drugbank.com/bio_entities/BE0004676TransporterHumansElectroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry (PubMed:10347222, PubMed:12403779, PubMed:14578046, PubMed:14736710). Mediates the sodium-dependent bicarbonate transport important for...
Polypeptides: Sodium bicarbonate cotransporter 3Synonyms: Solute carrier family 4 member 7, Sodium bicarbonate cotransporter 2DNA-3-methyladenine glycosylase
go.drugbank.com/bio_entities/BE0008954TargetEnzymeHumansHydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions
Polypeptides: DNA-3-methyladenine glycosylaseSynonyms: 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidaseSodium/hydrogen exchanger 3
go.drugbank.com/bio_entities/BE0009757TargetTransporterHumansPlasma membrane Na(+)/H(+) antiporter (PubMed:18829453, PubMed:26358773, PubMed:35613257). Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis...
Polypeptides: Sodium/hydrogen exchanger 3Synonyms: NHE-3, Na(+)/H(+) exchanger 3Toll-like receptor 3
go.drugbank.com/bio_entities/BE0010688TargetHumansKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is acti...
Polypeptides: Toll-like receptor 3Lysyl oxidase homolog 3
go.drugbank.com/bio_entities/BE0013537TargetHumansProtein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins (PubMed:17018530, PubMed:28065600). Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in pre...
Polypeptides: Lysyl oxidase homolog 3Synonyms: Lysyl oxidase-like protein 3Bromodomain-containing protein 3
go.drugbank.com/bio_entities/BE0014531TargetHumansChromatin reader that recognizes and binds acetylated histones, thereby controlling gene expression and remodeling chromatin structures (PubMed:18406326, PubMed:22464331, PubMed:27105114, PubMed:32895492). Recruits transcription factors ...
Polypeptides: Bromodomain-containing protein 3Lysophosphatidic acid receptor 3
go.drugbank.com/bio_entities/BE0020529TargetHumansReceptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins
Polypeptides: Lysophosphatidic acid receptor 3Synonyms: LPA-3, LPA receptor 3De Novo Triacylglycerol Biosynthesis TG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)/18:3(9Z,12Z,15Z))
smpdb.ca/view/SMP0016120MetabolicThe enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic
Enzymes: 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic