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Displaying results 81 - 90 of 2763 in total
  1. Target

    Cytochrome c-552

    go.drugbank.com/bio_entities/BE0001805
    TargetThermus thermophilus

    This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus.

    Polypeptides: Cytochrome c-552
  2. Target

    Apolipoprotein C-II

    go.drugbank.com/bio_entities/BE0008879
    TargetHumans

    Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase.

    Polypeptides: Apolipoprotein C-II
  3. Target

    C-terminal-binding protein 1

    go.drugbank.com/bio_entities/BE0002624
    TargetHumans

    Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tis...

    Polypeptides: C-terminal-binding protein 1
  4. Target

    C-terminal-binding protein 2

    go.drugbank.com/bio_entities/BE0013651
    TargetHumans

    Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity)

    Polypeptides: C-terminal-binding protein 2
  5. Target

    Prelamin-A/C

    go.drugbank.com/bio_entities/BE0010877
    TargetHumans

    Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner … Also involved in DNA repair: recruited by DNA repair proteins XRCC4 and IFFO1 to the DNA double-strand breaks (DSBs) to prevent chromosome translocation by immobilizing broken DNA ends (PubMed:31548606

    Polypeptides: Prelamin-A/CFunction: identical protein binding
  6. Target

    C-type lectin domain family 4 member C

    go.drugbank.com/bio_entities/BE0010522
    TargetHumans

    May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed:11748283)

    Polypeptides: C-type lectin domain family 4 member CSynonyms: C-type lectin superfamily member 7
  7. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A recepto...

    Polypeptides: Inactive phospholipase C-like protein 1Synonyms: Phospholipase C-related but catalytically inactive protein, Phospholipase C-deleted in lung carcinoma
  8. Target

    Fumarate reductase subunit C

    go.drugbank.com/bio_entities/BE0003961
    TargetEscherichia coli (strain K12)

    Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anch...

    Polypeptides: Fumarate reductase subunit CSynonyms: Fumarate reductase 15 kDa hydrophobic protein, QFR subunit C
  9. Target

    ATP synthase subunit c

    go.drugbank.com/bio_entities/BE0004748
    TargetMycobacterium tuberculosis

    F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. … During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

    Polypeptides: ATP synthase subunit cSynonyms: Lipid-binding protein, F-ATPase subunit c
  10. Target

    Proto-oncogene c-Rel

    go.drugbank.com/bio_entities/BE0010782
    TargetHumans

    NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. … The NF-kappa-B heterodimer RELA/p65-c-Rel is a transcriptional activator

    Polypeptides: Proto-oncogene c-Rel