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Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0000570DiseaseMethionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood. … It is caused by a mutation in the MTR gene which encodes the enzyme methionine synthase.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreAtropine
go.drugbank.com/drugs/DB00572ApprovedInvestigationalVet approvedOral atropine is only available in combination products. … [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675]
Products: Atropin Accord 0,1 mg/ml Injektionslösung in einer Fertigspritze, Atropinsulfat Aguettant 0,1 mg/ml Injektionslösung in FertigspritzeHomocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
smpdb.ca/view/SMP0125684DiseaseMethionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood. … It is caused by a mutation in the MTR gene which encodes the enzyme methionine synthase.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreLong-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (Fatty Acid Elongation in Mitochondria)
smpdb.ca/view/SMP0125748DiseaseThe estimated birth prevalence of LCHADD is 1 in 62 000 in Northern European individuals. The worldwide birth prevalence is estimated at 1 in 250 000. … MCADD is an autosomal recessive disorder associated with a mutation in the enzyme known as hydroxyacyl-CoA dehydrogenase (HADHA).
Golimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationaltreatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate
Products: SIMPONI 100MG ILO IN FER, SIMPONI 50MG ILO IN FERCefazolin
go.drugbank.com/drugs/DB01327ApprovedInvestigationalIt attains high serum levels and is excreted quickly via the urine.
Mixtures: CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET, CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETProducts: Cefazolin In Dextrose Injection, USP, REBASİN 1000 MG IM/IV ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acidFollitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalFollitropin beta is produced in genetically engineered Chinese hamster cell lines (CHO). … Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility.
Mixtures: Pergoveris solution for injection in pre-filled pen, MENOPUR 150 IU IM VE SC ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 5 ADETProducts: PUREGON SOLUTION FOR INJECTION IN CARTRIDGES 600 IU, PUREGON SOLUTION FOR INJECTION IN VIALS 50 IU/0.5mLFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.
Products: ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML, Zarzio 48 MU/0.5 ml solution for injection or infusion in pre-filled syringeHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigational[A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Mixtures: TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, TWINRIX PEDİATRİK IM 0.5 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖRProducts: AVAXIM-SUSPENSION FOR INJ IN A PREFILLED SYRINGE, AVAXIM Injektionssuspension in einer Fertigspritze