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Displaying results 891 - 900 of 10000 in total
  1. Target

    DNA-binding transcriptional regulator NtrC

    go.drugbank.com/bio_entities/BE0001282
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open p...

    Synonyms: Nitrogen regulator I, Nitrogen regulation protein NR(I)
  2. Target

    Apolipoprotein L1

    go.drugbank.com/bio_entities/BE0009069
    TargetHumans

    May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in kil...

    Synonyms: ApoL-I, Apolipoprotein L-I
  3. Target

    Geranylgeranyl transferase type-1 subunit beta

    go.drugbank.com/bio_entities/BE0001142
    TargetHumans

    Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include...

    Synonyms: GGTase-I-beta, Geranylgeranyl transferase type I subunit beta
  4. Target

    Cysteine dioxygenase type 1

    go.drugbank.com/bio_entities/BE0000569
    TargetEnzymeHumans

    Rate-limiting enzyme of the cysteine catabolic process to taurine, which catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen

    Synonyms: CDO-I, Cysteine dioxygenase type I
  5. Drug

    Dipropylene glycol

    go.drugbank.com/drugs/DB14140
    Investigational

    Synonyms: 4-Oxa-2,6-heptandiol, 1,1'-Oxybis(2-propanol)Products: Abelia pomegranate bounce up mask, Dr.g A-clear Balancing Moisturizer
  6. Drug

    Montelukast

    go.drugbank.com/drugs/DB00471
    ApprovedInvestigational

    Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product.

    Mixtures: BROCRIPTIN® 10 MG/ 5 MG, GLEMONT L® TABLETAS RECUBIERTASCategories: Agents to Treat Airway Disease, Cytochrome P-450 Substrates
  7. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring. … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms.

    Mixtures: DOLORSIN® FEM CAPSULA DURA CON CONTENIDO LIQUIDO, BIPASMIN COMPUESTO NSynonyms: N-butylscopolammonium, N-butylscopolammonium ion
  8. Indication

    Non-Hodgkin's Lymphoma (NHL)

    go.drugbank.com/conditions/DBCOND0030854
    Drugs: Bleomycin · Chlorambucil · Cladribine · Cyclophosphamide · Cytarabine · Daunorubicin +8 more
    Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)
  9. Target

    Nitric oxide synthase, inducible

    go.drugbank.com/bio_entities/BE0000005
    TargetEnzymeHumans

    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7504305, PubMed:7531687, PubMed:7544004, PubMed:7682706). … In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).

    Synonyms: Inducible NO synthase
  10. Drug

    Nicotinamide Mononucleotide

    go.drugbank.com/drugs/DB03227
    Investigational

    A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem] … 3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt.

    Products: Reus Nr