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Bevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigationalbevacizumab a therapeutic role in both oncology and ophthalmology. … [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target.
Synonyms: Bei Fa Zhu DankangProducts: BEVAX 100MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, BEVAX 400MG/16 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Products: ORALLI LW®Cimetidine
go.drugbank.com/drugs/DB00501ApprovedInvestigationalA histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. … It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Synonyms: N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidineProducts: Cimetidine in Sodium Chloride, Tagamet Inj 150mg/mlLinear primary-alkylsulfatase
go.drugbank.com/bio_entities/BE0003744TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)In addition, contributes to the in vivo virulence of P.aeruginosa by playing a central role in the degradation of mucin, a glycoprotein that is the primary component of the mucus overlaying the host epithelial … Plays a role in the degradation of both protein and carbohydrate moieties in mucin via the release of sulfate from mucin, D-galactose 6-sulfate (Gal-6S) and N-acetyl-D-glucosamine 6-sulfate (GlcNAc-6S)
Polypeptides: Linear primary-alkylsulfataseSynonyms: Type III linear primary-alkylsulfataseOligospermia
go.drugbank.com/conditions/DBCOND0001337Drugs: MesteroloneSynonyms: Decline in sperm countFolic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible for numerous adverse side effects.
Mixtures: Formula F L W, Multi II IV Vi TabSynonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acidTrastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationalProduced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody [A40276] that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular … Herzuma (trastuzumab-pkrb) is a biosimilar drug approved in December 2018 for the treatment of HER2-overexpressing breast cancer.
Products: HERZUMA 150 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET, CANHERA 150 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETLeg cramps
go.drugbank.com/conditions/DBCOND0093960Drugs: DiltiazemSynonyms: Cramps in legs, Muscle cramps in legDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Tim-Dor-Lat, Tim-Brim-Dor-LatProducts: Dorzo-Vision sine 20 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, DORZOLAMID AL 20 MG/ML